Abstract：
Ormosia hosiei Hemsl. et Wils. is an economical and medicinal plant, increasingly cultivated in China; however, its branches and leaves are often pruned as waste. This is the first study focused on the phytochemical profiles and antioxidant, anti-α-glucosidase, anti-tyrosinase, and anti-neuroinflammatory activities of the branches and leaves of O. hosiei. Herein, thirty-seven characteristic compounds were identified by UPLC-MS/MS and twelve were detected for the first time in O. hosiei. Twenty-seven phenolics were further quantified and significant differences in phenolic compositions between the branches and leaves of O. hosiei were observed. The ethanol extracts exhibited promising antioxidant, anti-α-glucosidase, anti-tyrosinase, and anti-neuroinflammatory effects, and the bioactivities significantly correlated with total phenolic content and twelve individual phenolics. Naringin, genistein, vitexin, vitexin-2-O-rhamnoside, syringaresinol and syringaresinol-4-O-β-D-glucopyranoside can be considered potential quality markers of O. hosiei. Our results provided solid evidence that the branches and leaves of O. hosiei deserve more attention and exploitation, considering the potential to be developed as functional foods or herbal medicines.
摘要：
OrmosiahosieiHemsl.威尔斯。是一种经济和药用植物，越来越多的种植在中国；然而，它的树枝和树叶经常被修剪成废物。这是第一个专注于植物化学特征和抗氧化剂的研究，抗α-葡萄糖苷酶，抗酪氨酸酶,和O.hosiei的枝叶的抗神经炎活性。在这里，通过UPLC-MS/MS鉴定出37个特征化合物，在O.hosiei中首次检测到12个。进一步量化了27种酚类物质，并观察到O.hosiei的树枝和叶子之间的酚类成分存在显着差异。乙醇提取物表现出有希望的抗氧化剂，抗α-葡萄糖苷酶，抗酪氨酸酶,和抗神经炎症作用，生物活性与总酚含量和12种单独的酚类物质显着相关。柚林宁,Genistein,vitexin,vitexin-2-O-鼠李糖苷，丁香雌酚和丁香雌酚-4-O-β-D-吡喃葡萄糖苷可以被认为是O.hosiei的潜在质量标志物。我们的研究结果提供了确凿的证据，表明O.hosiei的枝叶值得更多的关注和开发，考虑到作为功能性食品或草药开发的潜力。
