关键词: Anterior segment optical coherence tomography Central toxic keratopathy Photorefractive keratectomy

来  源:   DOI:10.4103/joco.joco_342_21   PDF(Pubmed)

Abstract:
UNASSIGNED: To report the clinical findings of unilateral central toxic keratopathy (CTK) associated with inadvertent exposure to topical minoxidil 5% solution 1 day after bilateral photorefractive keratectomy (PRK).
UNASSIGNED: Anterior segment slit-lamp photography, anterior segment optical coherence tomography (AS-OCT), pachymetry map, epithelial map, and manifest refractions were recorded.
UNASSIGNED: This is a case of a 27-year-old male who underwent bilateral PRK and presented 5 days after surgery with the complaint of acute decreased visual acuity in the left eye (LE). His LE was reportedly exposed to topical ethanol-based minoxidil 5% on postoperative day 1, which he was using as a posthair transplant treatment. Clinical examination showed hyperopic shift, poor visual acuity, central corneal opacity, epithelial irregularity, central corneal thinning, and flattening on AS-OCT. These findings were consistent with a diagnosis of CTK. The patient was monitored with conservative treatment and demonstrated full recovery after 6 months.
UNASSIGNED: It is recommended to warn patients who have undergone refractive surgery concerning the use of ethanol-containing agents, such as minoxidil solution, because of the possible risk of CTK, a complication not formally recognized.
摘要:
UNASSIGNED:报告与双侧屈光性角膜切除术(PRK)后1天意外暴露于局部米诺地尔5%溶液相关的单侧中心性角膜病变(CTK)的临床发现。
UNASSIGNED:前段裂隙灯摄影,眼前节光学相干断层扫描(AS-OCT),测厚图,上皮图,并记录了明显的折射。
UNASSIGNED:这是一例27岁男性患者,接受了双侧PRK,术后5天表现为左眼视力(LE)急性下降。据报道,他的LE在术后第1天暴露于局部乙醇基米诺地尔5%,他将其用作移植后治疗。临床检查显示远视移位,视力差,中央角膜混浊,上皮不规则,中央角膜变薄,在AS-OCT上变平。这些发现与CTK的诊断一致。患者接受保守治疗监测,6个月后完全康复。
未经评估:建议警告接受过屈光手术的患者使用含乙醇的药物,比如米诺地尔溶液,因为CTK的可能风险,没有正式承认的并发症。
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