{Reference Type}: Case Reports
{Title}: Topical Minoxidil Solution-Induced Central Toxic Keratopathy following Photorefractive Keratectomy: A Case Study.
{Author}: Mohammadpour M;Khorrami-Nejad M;Heirani M;Moshirfar M;
{Journal}: J Curr Ophthalmol
{Volume}: 34
{Issue}: 3
{Year}: Jul-Sep 2022
暂无{DOI}: 10.4103/joco.joco_342_21
{Abstract}: <B>UNASSIGNED: </B>To report the clinical findings of unilateral central toxic keratopathy (CTK) associated with inadvertent exposure to topical minoxidil 5% solution 1 day after bilateral photorefractive keratectomy (PRK).<BR><B>UNASSIGNED: </B>Anterior segment slit-lamp photography, anterior segment optical coherence tomography (AS-OCT), pachymetry map, epithelial map, and manifest refractions were recorded.<BR><B>UNASSIGNED: </B>This is a case of a 27-year-old male who underwent bilateral PRK and presented 5 days after surgery with the complaint of acute decreased visual acuity in the left eye (LE). His LE was reportedly exposed to topical ethanol-based minoxidil 5% on postoperative day 1, which he was using as a posthair transplant treatment. Clinical examination showed hyperopic shift, poor visual acuity, central corneal opacity, epithelial irregularity, central corneal thinning, and flattening on AS-OCT. These findings were consistent with a diagnosis of CTK. The patient was monitored with conservative treatment and demonstrated full recovery after 6 months.<BR><B>UNASSIGNED: </B>It is recommended to warn patients who have undergone refractive surgery concerning the use of ethanol-containing agents, such as minoxidil solution, because of the possible risk of CTK, a complication not formally recognized.