Abstract：
Resection of malignant tumors located in the anterior and middle fossae of the skull base requires thorough anatomical knowledge, as well as experience regarding the possible reconstructive options to resolve the resulting defects. The anatomical and functional relevance of the region, the complexity of the defects requiring reconstruction and the potential complications that can occur, represent a true challenge for the surgical team. The goal of this study is to describe the microsurgical reconstructive techniques available, their usefulness and postoperative complications, in patients with malignant tumors involving the skull base.
This observational, retrospective study, included all patients who underwent surgery for malignant craniofacial tumors from January 1st, 2009 to January 1st, 2019 at a University Hospital in Argentina. Only patients who required reconstruction of the resulting defect with a free flap were included.
Twenty-four patients required reconstruction with FF; 14 were male (58.3%) and mean age was 54.9 years. Sarcoma was the most frequent tumor histology. Free flaps used were the following: anterolateral thigh, rectus abdominis, radial, latissimus dorsi, iliac crest and fibular. Complications occurred in 6 cases and no deaths were reported in the study group.
Free flaps are considered one of the preferable choices of treatment for large skull base defects. In spite of the complexity of the technique and the learning curve required, free flaps have shown to be safe, with a low rate of serious complications. For these patients, the surgical resolution should be performed by a multidisciplinary team.
This observational, retrospective study, included all patients who underwent surgery for malignant craniofacial tumors from January 1st, 2009 to January 1st, 2019 at a University Hospital in Argentina. Only patients who required reconstruction of the resulting defect with a free flap were included.
Twenty-four patients required reconstruction with FF; 14 were male (58.3%) and mean age was 54.9 years. Sarcoma was the most frequent tumor histology. Free flaps used were the following: anterolateral thigh, rectus abdominis, radial, latissimus dorsi, iliac crest and fibular. Complications occurred in 6 cases and no deaths were reported in the study group.
Free flaps are considered one of the preferable choices of treatment for large skull base defects. In spite of the complexity of the technique and the learning curve required, free flaps have shown to be safe, with a low rate of serious complications. For these patients, the surgical resolution should be performed by a multidisciplinary team.
摘要：
背景：切除位于颅底前中窝的恶性肿瘤需要彻底的解剖学知识，以及关于解决由此产生的缺陷的可能的重建选择的经验。该区域的解剖和功能相关性，需要重建的缺陷的复杂性和可能发生的潜在并发症，对手术团队来说是一个真正的挑战。这项研究的目的是描述可用的显微外科重建技术，它们的有用性和术后并发症，涉及颅底的恶性肿瘤患者。
方法：这种观察，回顾性研究,包括从1月1日起接受恶性颅面肿瘤手术的所有患者，2009年1月1日,2019年在阿根廷大学医院。仅包括需要用游离皮瓣重建所得缺损的患者。
结果：24例患者需要FF重建；14例为男性（58.3%），平均年龄为54.9岁。肉瘤是最常见的肿瘤组织学。使用的游离皮瓣如下：股前外侧，腹直肌,径向,背阔肌,髂骨和腓骨。研究组发生并发症6例，无死亡报告。
结论：游离皮瓣被认为是治疗大型颅底缺损的首选方法之一。尽管技术的复杂性和所需的学习曲线，自由襟翼已经证明是安全的，严重并发症发生率低。对于这些患者来说,手术解决方案应由多学科团队进行.
方法：这种观察，回顾性研究,包括从1月1日起接受恶性颅面肿瘤手术的所有患者，2009年1月1日,2019年在阿根廷大学医院。仅包括需要用游离皮瓣重建所得缺损的患者。
结果：24例患者需要FF重建；14例为男性（58.3%），平均年龄为54.9岁。肉瘤是最常见的肿瘤组织学。使用的游离皮瓣如下：股前外侧，腹直肌,径向,背阔肌,髂骨和腓骨。研究组发生并发症6例，无死亡报告。
结论：游离皮瓣被认为是治疗大型颅底缺损的首选方法之一。尽管技术的复杂性和所需的学习曲线，自由襟翼已经证明是安全的，严重并发症发生率低。对于这些患者来说,手术解决方案应由多学科团队进行.
