关键词: irradiation oncology orbit pathology sarcoma

Mesh : Adult Female Humans Male Middle Aged Magnetic Resonance Imaging Neoplasms, Radiation-Induced / diagnosis Orbital Neoplasms / radiotherapy diagnostic imaging pathology Sarcoma / radiotherapy Tomography, X-Ray Computed

来  源:   DOI:10.1080/01676830.2022.2160766

Abstract:
UNASSIGNED: To describe a series of eight adult patients with primary orbital sarcoma and to review the existing literature on orbital sarcoma and post-irradiation sarcoma.
UNASSIGNED: Report of eight cases and literature review.
UNASSIGNED: We report eight cases of primary orbital sarcoma, three of which were radiation-induced. Only one patient had a history of retinoblastoma. The most common presentations were painful proptosis and reduced vision. Most tumours arose in the extraconal compartment. The overall median age at diagnosis was 50 years. The pathology comprised a diverse group of tumours. Treatment and outcome varied between patients and their clinical circumstances.
UNASSIGNED: Adult primary orbital sarcomas are rare. They can comprise a variety of tumour types and are difficult to treat. Irradiation is a significant risk factor, and the incidence of post-irradiation sarcoma of the orbit may be increasing due to the widespread use of radiotherapy and improved survival of patients with cancer. Post-irradiation sarcoma should be considered in the differential diagnosis of an orbital space-occupying lesion in a patient with a history of radiotherapy.
摘要:
UNASSIGNED:描述一系列8例成人原发性眼眶肉瘤患者,并回顾关于眼眶肉瘤和放疗后肉瘤的现有文献。
UNASSIGNED:8例报告并文献复习。
未经证实:我们报告8例原发性眼眶肉瘤,其中三个是辐射诱导的。只有一名患者有视网膜母细胞瘤病史。最常见的表现是疼痛性眼球突出和视力下降。大多数肿瘤出现在外侧隔室。诊断时的总体中位年龄为50岁。病理学包括不同组的肿瘤。治疗和结果因患者及其临床情况而异。
未经证实:成人原发性眼眶肉瘤是罕见的。它们可以包括多种肿瘤类型并且难以治疗。辐射是一个重要的危险因素,由于放疗的广泛使用和癌症患者生存率的提高,照射后眼眶肉瘤的发生率可能会增加。在有放疗史的患者的眼眶占位性病变的鉴别诊断中,应考虑照射后肉瘤。
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