Abstract：
To evaluate the safety and clinical effectiveness of transoral laser microsurgery (TLM) with potassium-titanyl-phosphate (KTP) laser ablation for glottic neoplasms.
MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
A systematic review and meta-analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early-stage glottic neoplasms.
Eight studies were included. After an average follow-up of 3.3 years, the overall survival and disease-free survival for patients who underwent KTP were 90.7% (95% CI 85%-96.5%) and 98.5% (95% CI 97.3%-99.8%), respectively. In the single-arm meta-analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%-12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single-arm meta-analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one-year follow-up, respectively.
KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806-1814, 2023.
MEDLINE via PubMed, SCOPUS, Web of Science, and Cochrane Library.
A systematic review and meta-analysis of studies assessing the safety and efficacy of KTP laser therapy in patients with early-stage glottic neoplasms.
Eight studies were included. After an average follow-up of 3.3 years, the overall survival and disease-free survival for patients who underwent KTP were 90.7% (95% CI 85%-96.5%) and 98.5% (95% CI 97.3%-99.8%), respectively. In the single-arm meta-analysis, the pooled estimate of recurrence was 7.7% (95% CI 3.4%-12%). The overall voice handicap index (VHI) estimate attributed to KTP in the single-arm meta-analysis was 6.76 (95% CI [3.05, 10.48]) and 5.21 (95% CI [2.86, 7.56]) within 6 months and after a one-year follow-up, respectively.
KTP laser ablation is a safe and effective method for treating patients with early glottic neoplasms. Laryngoscope, 133:1806-1814, 2023.
摘要：
目的：评估经口激光显微手术（TLM）联合磷酸钛氧钾（KTP）激光消融治疗声门肿瘤的安全性和临床有效性。
方法：通过PubMed的MEDLINE，Scopus,WebofScience,科克伦图书馆
方法：评估KTP激光治疗早期声门肿瘤患者的安全性和有效性的研究的系统评价和荟萃分析。
结果：纳入了8项研究。经过平均3.3年的随访，接受KTP的患者的总生存率和无病生存率分别为90.7%(95%CI85%-96.5%)和98.5%(95%CI97.3%-99.8%),分别。在单臂荟萃分析中，复发的汇总估计值为7.7%(95%CI3.4%-12%).单臂荟萃分析中归因于KTP的总体语音障碍指数（VHI）估计值在6个月内和一年随访后分别为6.76（95％CI[3.05，10.48]）和5.21（95％CI[2.86，7.56]）。分别。
结论：KTP激光消融治疗早期声门型肿瘤是一种安全有效的方法。喉镜,2023年。
方法：通过PubMed的MEDLINE，Scopus,WebofScience,科克伦图书馆
方法：评估KTP激光治疗早期声门肿瘤患者的安全性和有效性的研究的系统评价和荟萃分析。
结果：纳入了8项研究。经过平均3.3年的随访，接受KTP的患者的总生存率和无病生存率分别为90.7%(95%CI85%-96.5%)和98.5%(95%CI97.3%-99.8%),分别。在单臂荟萃分析中，复发的汇总估计值为7.7%(95%CI3.4%-12%).单臂荟萃分析中归因于KTP的总体语音障碍指数（VHI）估计值在6个月内和一年随访后分别为6.76（95％CI[3.05，10.48]）和5.21（95％CI[2.86，7.56]）。分别。
结论：KTP激光消融治疗早期声门型肿瘤是一种安全有效的方法。喉镜,2023年。
