PDF(Pubmed)
Abstract：
UNASSIGNED: Regular Baduanjin exercise training has been shown to be beneficial to the physical and cognitive health of older adults, but the underlying mechanisms remain to be investigated. This study examined the influence of Baduanjin on cerebral hemodynamics in community-dwelling older adults with cognitive frailty.
UNASSIGNED: Randomized controlled trial.
UNASSIGNED: A total of 102 eligible participants were randomly allocated into the Baduanjin exercise intervention group (BEG) or usual physical activity control group (CG) for 24 weeks. Cerebral hemodynamic parameters of bilateral middle/anterior cerebral artery and basilar artery, cognitive ability and physical frailty were assessed using Transcranial Doppler (TCD), Montreal Cognitive Assessment (MoCA) and Edmonton Frailty Scale (EFS) at baseline and 24 weeks post-intervention.
UNASSIGNED: After 24 weeks intervention, the changes in peak systolic velocity (PSV), mean blood flow velocity (MBFV), and end diastolic velocity (EDV) in the right middle cerebral artery and basilar artery were better in the BEG than in the CG; the increase in MoCA scores and the decrease in EFS scores were significantly higher in the BEG than in the CG. Moreover, the interaction of exercise and time on those variables showed obvious significance.
UNASSIGNED: The 24 weeks Baduanjin exercise training had a positive beneficial effect on cerebral blood flow in community-dwelling older adults with cognitive frailty. This may be a potential mechanism by which Baduanjin exercise improves the cognitive frailty in older adults.
UNASSIGNED: Chinese Clinical Trial Registry, ChiCTR1800020341.
UNASSIGNED: December 25, 2018, http://www.chictr.org.cn/showproj.aspx?proj=29846.
UNASSIGNED: Randomized controlled trial.
UNASSIGNED: A total of 102 eligible participants were randomly allocated into the Baduanjin exercise intervention group (BEG) or usual physical activity control group (CG) for 24 weeks. Cerebral hemodynamic parameters of bilateral middle/anterior cerebral artery and basilar artery, cognitive ability and physical frailty were assessed using Transcranial Doppler (TCD), Montreal Cognitive Assessment (MoCA) and Edmonton Frailty Scale (EFS) at baseline and 24 weeks post-intervention.
UNASSIGNED: After 24 weeks intervention, the changes in peak systolic velocity (PSV), mean blood flow velocity (MBFV), and end diastolic velocity (EDV) in the right middle cerebral artery and basilar artery were better in the BEG than in the CG; the increase in MoCA scores and the decrease in EFS scores were significantly higher in the BEG than in the CG. Moreover, the interaction of exercise and time on those variables showed obvious significance.
UNASSIGNED: The 24 weeks Baduanjin exercise training had a positive beneficial effect on cerebral blood flow in community-dwelling older adults with cognitive frailty. This may be a potential mechanism by which Baduanjin exercise improves the cognitive frailty in older adults.
UNASSIGNED: Chinese Clinical Trial Registry, ChiCTR1800020341.
UNASSIGNED: December 25, 2018, http://www.chictr.org.cn/showproj.aspx?proj=29846.
摘要：
UNASSIGNED：定期八段锦运动训练已被证明对老年人的身体和认知健康有益，但潜在的机制仍有待研究。这项研究研究了八段锦对认知脆弱的社区居住老年人脑血流动力学的影响。
未经授权：随机对照试验。
UNASSIGNED：总共102名符合条件的参与者被随机分配到八段锦运动干预组（BEG）或常规体力活动对照组（CG），为期24周。双侧大脑中/前动脉和基底动脉的脑血流动力学参数，使用经颅多普勒（TCD）评估认知能力和身体虚弱，基线和干预后24周的蒙特利尔认知评估（MoCA）和埃德蒙顿脆弱量表（EFS）。
未经评估：干预24周后，收缩期峰值速度（PSV）的变化，平均血流速度（MBFV），BEG中右大脑中动脉和基底动脉的舒张末期速度（EDV）优于CG；BEG中MoCA评分的升高和EFS评分的降低明显高于CG。此外，运动和时间对这些变量的交互作用具有明显的意义。
UNASSIGNED：24周的八段锦运动训练对认知虚弱的社区居住老年人的脑血流量有积极的有益影响。这可能是八段锦运动改善老年人认知虚弱的潜在机制。
未经批准：中国临床试验注册中心，ChiCTR1800020341。
UNASSIGNED：2018年12月25日，http://www.chictr.org.cn/showproj.aspx?proj=29846。
未经授权：随机对照试验。
UNASSIGNED：总共102名符合条件的参与者被随机分配到八段锦运动干预组（BEG）或常规体力活动对照组（CG），为期24周。双侧大脑中/前动脉和基底动脉的脑血流动力学参数，使用经颅多普勒（TCD）评估认知能力和身体虚弱，基线和干预后24周的蒙特利尔认知评估（MoCA）和埃德蒙顿脆弱量表（EFS）。
未经评估：干预24周后，收缩期峰值速度（PSV）的变化，平均血流速度（MBFV），BEG中右大脑中动脉和基底动脉的舒张末期速度（EDV）优于CG；BEG中MoCA评分的升高和EFS评分的降低明显高于CG。此外，运动和时间对这些变量的交互作用具有明显的意义。
UNASSIGNED：24周的八段锦运动训练对认知虚弱的社区居住老年人的脑血流量有积极的有益影响。这可能是八段锦运动改善老年人认知虚弱的潜在机制。
未经批准：中国临床试验注册中心，ChiCTR1800020341。
UNASSIGNED：2018年12月25日，http://www.chictr.org.cn/showproj.aspx?proj=29846。
