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Abstract：
Ameloblastic carcinoma is a locally aggressive odontogenic tumor that most commonly affects young and middle-aged adults. Metastatic disease may develop insidiously and manifest months or years after the initial diagnosis. Herein, we describe the clinical, imaging, and pathologic findings of a 31-year-old male who presented to the emergency department with headache and vision loss of 3 months duration and was subsequently found to have ameloblastic carcinoma with hepatic metastases. Initial computed tomography (CT) and magnetic resonance imaging revealed a multilocular cystic mass with avidly-enhancing nodular soft-tissue components associated with the right temporal fossa. Histologic examination of a tissue sample showed findings consistent with ameloblastic carcinoma. An initial staging CT scan showed several small hepatic cystic lesions. Follow-up surveillance imaging showed interval growth. A subsequent biopsy of a hepatic lesion showed findings compatible with metastatic ameloblastic carcinoma. The patient was started on systemic chemotherapy with evidence of disease progression at 1-year follow-up.
摘要：
成釉细胞癌是一种局部侵袭性牙源性肿瘤，最常见于年轻人和中年人。转移性疾病可能会在最初诊断后数月或数年内隐匿发展并表现出来。在这里，我们描述了临床，成像,以及一名31岁男性因头痛和视力丧失3个月到急诊科就诊，随后被发现患有成釉细胞癌伴肝转移的病理结果。初始计算机断层扫描（CT）和磁共振成像显示多房性囊性肿块，与右颞窝相关的结节状软组织成分强烈增强。组织样本的组织学检查显示发现与成釉细胞癌一致。初始分期CT扫描显示几个小的肝囊性病变。随访监测成像显示间隔增长。随后的肝病灶活检显示发现与转移性成釉细胞癌相符。患者开始接受全身化疗，随访1年有疾病进展的证据。
