{Reference Type}: Case Reports {Title}: Ameloblastic carcinoma with hepatic metastases: A case report and review of ameloblastomic carcinoma. {Author}: Hoehnle NS;Beutler BD;Ulanja MB;Rastegarpour A; {Journal}: J Clin Imaging Sci {Volume}: 12 {Issue}: 0 {Year}: 2022 暂无{DOI}: 10.25259/JCIS_115_2022 {Abstract}: Ameloblastic carcinoma is a locally aggressive odontogenic tumor that most commonly affects young and middle-aged adults. Metastatic disease may develop insidiously and manifest months or years after the initial diagnosis. Herein, we describe the clinical, imaging, and pathologic findings of a 31-year-old male who presented to the emergency department with headache and vision loss of 3 months duration and was subsequently found to have ameloblastic carcinoma with hepatic metastases. Initial computed tomography (CT) and magnetic resonance imaging revealed a multilocular cystic mass with avidly-enhancing nodular soft-tissue components associated with the right temporal fossa. Histologic examination of a tissue sample showed findings consistent with ameloblastic carcinoma. An initial staging CT scan showed several small hepatic cystic lesions. Follow-up surveillance imaging showed interval growth. A subsequent biopsy of a hepatic lesion showed findings compatible with metastatic ameloblastic carcinoma. The patient was started on systemic chemotherapy with evidence of disease progression at 1-year follow-up.