PDF(Pubmed)
Abstract：
UNASSIGNED: to describe a case of severe sepsis and complicated bacteremia caused by Arcanobacterium haemolyticum and review similar cases in the literature.
UNASSIGNED: A 26-year-old gentleman with a history of epilepsy presented with symptoms of sore throat, productive cough, periumbilical abdominal pain, watery diarrhea, nausea and vomiting, subjective fevers along with progressive jaundice for seven days. The patient had acute fulminant liver failure, septic shock, and Multi-organ failure. He required vasopressors, underwent intubation, and had grown Arcanobacterium haemolyticum in the blood and Bronchoalveolar lavage samples. He developed a peritonsillar abscess and cavitary pneumonia and required chest tube drainage followed by thoracotomy for hemothorax. The patient improved on Ampicillin-Sulbactam treatment and was treated with a total antibiotic duration of 6 weeks. He fully improved on post-discharge follow-up.
UNASSIGNED: Arcanobacterium haemolyticum is a Gram-positive (sometimes Gram variable), catalase-negative facultatively anaerobic, non-motile, non-spore-forming, and variably β-hemolytic and is known to be a cause of pharyngitis and skin and soft tissue infections. Rarely A. Haemolyticum can be associated with severe systemic infections such as infective endocarditis, systemic abscesses, osteomyelitis, and septicemia. In previous literature reviews, the source of A. haemolyticum depended on the host, and pharyngeal and upper respiratory sources were likely to be associated with immunocompetent hosts.
UNASSIGNED: A. haemolyticum should be included in the differential diagnosis of bacterial pharyngitis complicated by severe systemic illness. Penicillins are the most commonly used antibiotics for treating A. haemolyticum bacteremia, and macrolides can be used for Penicillin\'s treatment failure.
UNASSIGNED: A 26-year-old gentleman with a history of epilepsy presented with symptoms of sore throat, productive cough, periumbilical abdominal pain, watery diarrhea, nausea and vomiting, subjective fevers along with progressive jaundice for seven days. The patient had acute fulminant liver failure, septic shock, and Multi-organ failure. He required vasopressors, underwent intubation, and had grown Arcanobacterium haemolyticum in the blood and Bronchoalveolar lavage samples. He developed a peritonsillar abscess and cavitary pneumonia and required chest tube drainage followed by thoracotomy for hemothorax. The patient improved on Ampicillin-Sulbactam treatment and was treated with a total antibiotic duration of 6 weeks. He fully improved on post-discharge follow-up.
UNASSIGNED: Arcanobacterium haemolyticum is a Gram-positive (sometimes Gram variable), catalase-negative facultatively anaerobic, non-motile, non-spore-forming, and variably β-hemolytic and is known to be a cause of pharyngitis and skin and soft tissue infections. Rarely A. Haemolyticum can be associated with severe systemic infections such as infective endocarditis, systemic abscesses, osteomyelitis, and septicemia. In previous literature reviews, the source of A. haemolyticum depended on the host, and pharyngeal and upper respiratory sources were likely to be associated with immunocompetent hosts.
UNASSIGNED: A. haemolyticum should be included in the differential diagnosis of bacterial pharyngitis complicated by severe systemic illness. Penicillins are the most commonly used antibiotics for treating A. haemolyticum bacteremia, and macrolides can be used for Penicillin\'s treatment failure.
摘要：
UNASSIGNED：描述一例由溶血性弧菌引起的严重败血症和复杂菌血症，并回顾文献中的类似病例。
未经证实：一位26岁有癫痫史的绅士出现喉咙痛的症状，生产性咳嗽,脐周腹痛,水样腹泻,恶心和呕吐，主观性发热伴进行性黄疸7天。病人患有急性暴发性肝功能衰竭,感染性休克,多器官衰竭。他需要血管加压药,接受了插管,并且在血液和支气管肺泡灌洗样本中生长了溶血弧菌。他发展为扁桃体周围脓肿和空洞性肺炎，需要胸腔引流，然后进行开胸手术治疗血胸。患者在氨苄西林-舒巴坦治疗后有所改善，并接受了6周的总抗生素治疗。他在出院后的随访中得到了充分的改善。
未经证实：溶血性弧菌是革兰氏阳性（有时是革兰氏变量），过氧化氢酶阴性兼性厌氧，不活动，非孢子形成，和可变的β-溶血，已知是咽炎和皮肤和软组织感染的原因。很少有A.溶血杆菌可能与严重的全身性感染有关，例如感染性心内膜炎。系统性脓肿,骨髓炎,和败血症。在以前的文献综述中，溶血芽孢杆菌的来源取决于宿主，咽部和上呼吸道源可能与有免疫能力的宿主有关。
未经评估：A.合并严重全身性疾病的细菌性咽炎的鉴别诊断应包括溶血病。青霉素是最常用的抗生素，用于治疗溶血芽孢杆菌菌血症，大环内酯类药物可用于青霉素治疗失败。
未经证实：一位26岁有癫痫史的绅士出现喉咙痛的症状，生产性咳嗽,脐周腹痛,水样腹泻,恶心和呕吐，主观性发热伴进行性黄疸7天。病人患有急性暴发性肝功能衰竭,感染性休克,多器官衰竭。他需要血管加压药,接受了插管,并且在血液和支气管肺泡灌洗样本中生长了溶血弧菌。他发展为扁桃体周围脓肿和空洞性肺炎，需要胸腔引流，然后进行开胸手术治疗血胸。患者在氨苄西林-舒巴坦治疗后有所改善，并接受了6周的总抗生素治疗。他在出院后的随访中得到了充分的改善。
未经证实：溶血性弧菌是革兰氏阳性（有时是革兰氏变量），过氧化氢酶阴性兼性厌氧，不活动，非孢子形成，和可变的β-溶血，已知是咽炎和皮肤和软组织感染的原因。很少有A.溶血杆菌可能与严重的全身性感染有关，例如感染性心内膜炎。系统性脓肿,骨髓炎,和败血症。在以前的文献综述中，溶血芽孢杆菌的来源取决于宿主，咽部和上呼吸道源可能与有免疫能力的宿主有关。
未经评估：A.合并严重全身性疾病的细菌性咽炎的鉴别诊断应包括溶血病。青霉素是最常用的抗生素，用于治疗溶血芽孢杆菌菌血症，大环内酯类药物可用于青霉素治疗失败。
