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Abstract：
POEMS syndrome is a plasma cell disease. Clinical manifestations and clinical onset are variable. In recent years, more and more cases of POEMS syndrome with cerebrovascular disease and ischemic stroke have been reported. However, it is rare for patients with POEMS syndrome to present with a cerebrovascular accident as the first clinical manifestation. We presented three cases of POEMS syndrome with cerebral infarction in different phases of the disease. We then searched the literature for studies involving POEMS syndrome complicated with cerebral infarction. There were 81 cases in total. In nine patients, cerebral infarctions occurred before polyneuropathy. Patients with cerebral infarction before polyneuropathy have better prognosis of POEMS than those with cerebral infarction after polyneuropathy.
摘要：
POEMS综合征是一种浆细胞疾病。临床表现和临床发作是可变的。近年来,越来越多的POEMS综合征合并脑血管疾病和缺血性卒中的病例被报道。然而,POEMS综合征患者很少以脑血管意外为首发临床表现。我们介绍了3例POEMS综合征在疾病的不同阶段伴有脑梗死的病例。然后，我们检索了涉及POEMS综合征并发脑梗死的研究文献。共81例。在9名患者中，脑梗死发生在多发性神经病之前。多发性神经病前脑梗死患者POEMS的预后优于多发性神经病后脑梗死患者。
