Abstract：
Reactive oxygen species and other free radicals cause oxidative stress which is the underlying pathogenesis of cellular injury in various neurological diseases. Molecular hydrogen therapy with its unique biological property of selectively scavenging pathological free radicals has demonstrated therapeutic potential in innumerable animal studies and some clinical trials. These studies have implicated several cellular pathways affected by hydrogen therapy in explaining its anti-inflammatory and antioxidative effects. This article reviews relevant animal and clinical studies that demonstrate neuroprotective effects of hydrogen therapy in stroke, neurodegenerative diseases, neurotrauma, and global brain injury.
摘要：
活性氧和其他自由基引起氧化应激，这是各种神经系统疾病中细胞损伤的潜在发病机制。分子氢疗法具有选择性清除病理性自由基的独特生物学特性，已在无数动物研究和一些临床试验中显示出治疗潜力。这些研究暗示了受氢疗法影响的几种细胞途径，以解释其抗炎和抗氧化作用。本文综述了证明氢疗法对中风的神经保护作用的相关动物和临床研究。神经退行性疾病，神经创伤,和全球脑损伤。
