PDF(Pubmed)
Abstract：
Normal development of the fovea begins before midgestation and continues for several years after birth. Foveal hypoplasia is a condition in which the foveal pit and the foveal avascular zone do not fully develop. Several diseases are known to be associated with foveal hypoplasia; however, a direct association between foveal hypoplasia and congenital rubella has not been stated so far. This report describes a case of foveal hypoplasia detected during adulthood in a patient with known fetal exposure to maternal rubella infection and several ocular features of congenital rubella syndrome, including microphthalmia, congenital cataract, and pigmentary retinopathy. During follow-up, the visual acuity and ocular fundus changes remained stable.
摘要：
中央凹的正常发育在妊娠中期之前开始，并在出生后持续数年。中央凹发育不全是中央凹窝和中央凹无血管区未完全发育的病症。已知几种疾病与中央凹发育不全有关；然而，到目前为止，还没有提到中央凹发育不全与先天性风疹之间的直接关联。本报告描述了一名已知胎儿暴露于母体风疹感染和先天性风疹综合征的几种眼部特征的患者在成年期发现的中央凹发育不全病例。包括小眼症,先天性白内障,和色素性视网膜病变.随访期间,视力和眼底变化保持稳定。
