与使用电子烟相关的健康影响和已知病理。
关键词: AEC, airway epithelial cells AM, alveolar macrophages BAL, bronchial alveolar lavage CC16, Clara cell protein 16 CM, cardiomyocyte CNS, central nervous system COPD, chronic obstructive pulmonary disease CS, cigarette smoke CSC, Cancer Stem Cell CYP, cytochrome P450 E-cigarettes E2F1, E2F transcription factor 1 EMT, epithelial-to-mesenchymal transition ENDS, electronic nicotine delivery system EVALI EVALI, e-cigarette or vaping product use-associated lung injury FDA, Food and Drug Administration FOXO3, forkhead box O3 HNSCC, head and neck squamous cancer cells HUVEC, human umbilical vein endothelial cells Health risks IL, interleukin LDL, low-density lipoprotein MCP-1, monocyte chemoattractant protein-1 MMP9, matrix metallopeptidase 9 MPP, Mycoplasma pneumoniae pneumonia NET, neutrophil extracellular traps NK, natural killer NOX, NADPH oxidase NQO-1, NAD(P)H quinone dehydrogenase 1 Nicotine Nrf2, nuclear factor erythroid 2-related factor 2 OGG1/2, 8-oxoguanine glycosylase OS, oxidative stress Oct4,, Octamer-binding transcription factor 4 PAFR, platelet-activating factor receptor PAHs, polycyclic aromatic hydrocarbons PG, propylene glycol ROS, reactive oxygen species Sox2,, SRY (sex determining region Y)-box 2 THC, Tetrahydrocannabinol TNF‐α, tumor necrosis factor alpha VAPI, vaping-associated pulmonary injury VG, vegetable glycerin Vaping XPC, xeroderma pigmentosum complementation group C Yap1, Yes associated protein 1 ZEB, zinc finger E-box binding homeobox ZO-1, zonula occludens-1 e-cigarettes, electronic cigarettes e-liquid, e-cigarette liquid e-vapor, e-cigarette vapor iPSC-EC, induced pluripotent stem cell-derived endothelial cells pAMPK, phospho-AMP-activated protein kinase
来 源:
DOI:10.1016/j.toxrep.2022.06.006
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