PDF(Pubmed)
Abstract：
UNASSIGNED: Molluscum contagiosum (MC) is a common self-limiting viral infection of the skin. Many therapeutic agents have been used for it with varying success rates.
UNASSIGNED: To evaluate and compare the efficacy and safety profile of topical 20% glycolic acid and 30% salicylic acid in the treatment of MC in pediatric patients.
UNASSIGNED: All patients of MC between 1 and 15 years of age attending the outpatient department of dermatology were randomized into two treatment groups A and B. Group A was treated with 20% glycolic acid solution, and group B was treated with 30% salicylic acid solution daily for 4 weeks. Parents of patients were instructed to apply the medication once daily at night for 1 h on the lesions only. The assessment of response and side effects were analyzed in all the patients weekly for 4 weeks during the daily treatment protocol. Follow-up was done monthly for 3 months after the completion of therapy.
UNASSIGNED: At the end of 4 weeks, group A patients (60 patients) were treated with 20% glycolic acid out of which 34 (56.66%) patients had a complete clearance of lesions. Group B patients were treated with 30% salicylic acid out of which 38 (63.33%) had a complete clearance of lesions. Secondary bacterial infection was the most common side effect followed by postinflammatory hyperpigmentation in both groups.
UNASSIGNED: 30% salicylic acid was found to be more effective and has less side-effect profile in the treatment of MC than 20% glycolic acid.
UNASSIGNED: To evaluate and compare the efficacy and safety profile of topical 20% glycolic acid and 30% salicylic acid in the treatment of MC in pediatric patients.
UNASSIGNED: All patients of MC between 1 and 15 years of age attending the outpatient department of dermatology were randomized into two treatment groups A and B. Group A was treated with 20% glycolic acid solution, and group B was treated with 30% salicylic acid solution daily for 4 weeks. Parents of patients were instructed to apply the medication once daily at night for 1 h on the lesions only. The assessment of response and side effects were analyzed in all the patients weekly for 4 weeks during the daily treatment protocol. Follow-up was done monthly for 3 months after the completion of therapy.
UNASSIGNED: At the end of 4 weeks, group A patients (60 patients) were treated with 20% glycolic acid out of which 34 (56.66%) patients had a complete clearance of lesions. Group B patients were treated with 30% salicylic acid out of which 38 (63.33%) had a complete clearance of lesions. Secondary bacterial infection was the most common side effect followed by postinflammatory hyperpigmentation in both groups.
UNASSIGNED: 30% salicylic acid was found to be more effective and has less side-effect profile in the treatment of MC than 20% glycolic acid.
摘要：
未经证实：传染性软疣（MC）是一种常见的皮肤自限性病毒感染。许多治疗剂已经以不同的成功率用于它。
UNASSIGNED：评估和比较20％乙醇酸和30％水杨酸局部治疗小儿MC的疗效和安全性。
UNASSIGNED：将所有1至15岁的MC患者随机分为A和B两个治疗组。A组用20％乙醇酸溶液治疗，B组每日给予30%水杨酸溶液治疗4周。指示患者的父母每天一次晚上仅在病变上施用药物1小时。在每日治疗方案期间，每周对所有患者进行4周的反应和副作用评估。治疗结束后每月随访3个月。
未经评估：在4周结束时，A组患者（60例）接受20％的乙醇酸治疗，其中34例（56.66％）患者的病变完全清除。B组患者接受30％水杨酸治疗，其中38例（63.33％）的病变完全清除。在两组中，继发细菌感染是最常见的副作用，其次是炎症后色素沉着过度。
UNASSIGNED：发现30％水杨酸比20％乙醇酸更有效，并且在MC的治疗中副作用更少。
UNASSIGNED：评估和比较20％乙醇酸和30％水杨酸局部治疗小儿MC的疗效和安全性。
UNASSIGNED：将所有1至15岁的MC患者随机分为A和B两个治疗组。A组用20％乙醇酸溶液治疗，B组每日给予30%水杨酸溶液治疗4周。指示患者的父母每天一次晚上仅在病变上施用药物1小时。在每日治疗方案期间，每周对所有患者进行4周的反应和副作用评估。治疗结束后每月随访3个月。
未经评估：在4周结束时，A组患者（60例）接受20％的乙醇酸治疗，其中34例（56.66％）患者的病变完全清除。B组患者接受30％水杨酸治疗，其中38例（63.33％）的病变完全清除。在两组中，继发细菌感染是最常见的副作用，其次是炎症后色素沉着过度。
UNASSIGNED：发现30％水杨酸比20％乙醇酸更有效，并且在MC的治疗中副作用更少。
