PDF(Pubmed)
Abstract：
Suicidal behavior is associated with deficits in cognitive control; however, suicidal ideation (SI), a key precursor to suicidal behavior, has been less consistently linked to neuropsychological functioning. Additionally, no study to date has examined attentional control capacities in relation to variability in suicidal ideation, defined as fluctuation in SI intensity and duration across short periods of time. Prior research suggests that suicidal individuals with highly variable SI experience greater stress-responsive increases in SI and cortisol, potentially raising risk for suicidal behavior. Here, we examined attentional control capacities associated with SI variability and severity in ninety-five subjects with major depressive disorder. Variability and severity of SI and depressive affect were quantified using Ecological Momentary Assessment (EMA) over a 7-day period. Participants completed the Continuous Performance Task (CPT) and a computerized Stroop task for assessment of attentional control. EMA SI variability was associated with greater attentional interference on the Stroop task, and this was not accounted for by severity of SI, concurrently assessed depressive affect, or baseline depression. CPT performance was not related to SI variability or intensity. Findings highlight the utility of EMA methods in characterizing patterned experiences of SI and suggest that attentional control deficits may contribute to these characteristic patterns.
摘要：
自杀行为与认知控制缺陷有关；然而，自杀意念（SI），自杀行为的关键前兆,与神经心理功能的联系不那么一致。此外,迄今为止，还没有一项研究检查了注意力控制能力与自杀意念变异性的关系，定义为SI强度和持续时间在短时间内的波动。先前的研究表明，具有高度可变SI的自杀个体经历了更大的SI和皮质醇的压力反应性增加，可能增加自杀行为的风险。这里,我们研究了95例重度抑郁症患者的注意力控制能力与SI变异性和严重程度相关。在7天的时间内，使用生态瞬时评估（EMA）对SI和抑郁影响的变异性和严重程度进行了量化。参与者完成了持续绩效任务（CPT）和计算机Stroop任务，以评估注意力控制。EMASI变异性与对Stroop任务的更大注意力干扰有关，这不是SI的严重程度，同时评估抑郁情绪，或基线抑郁。CPT表现与SI变异性或强度无关。研究结果强调了EMA方法在表征SI模式体验中的实用性，并表明注意力控制缺陷可能有助于这些特征模式。
