Abstract：
A reliable assessment of renal function is of paramount importance in several clinical assets in order to tailor a personalized medical approach. CKD classification system, created in 2002 by the National Kidney Foundation-sponsored Kidney Disease Outcomes Quality Initiative and then implemented in the following years by the K-DIGO guidelines, offered clinicians a new strategy to better identify nephrological patients at low or high risk to develop renal insufficiency, in order to avoid the progression to end-stage renal disease. However, the criteria used to create this classification did not consider some important aspects related to renal histology and glomerular filtration rate measurement, resulting in a possible over- or underestimation of the real established renal damage. In this mini-review, we will summarize the most relevant shortcomings in the CKD classifications, which can create misleading diagnosis in daily clinical practice.
摘要：
为了定制个性化医疗方法，对肾功能的可靠评估在几种临床资产中至关重要。CKD分类系统，由国家肾脏基金会赞助的肾脏疾病结果质量倡议于2002年创建，然后在接下来的几年中由K-DIGO指南实施，为临床医生提供了一种新的策略，以更好地识别患有肾功能不全的高风险或低风险的肾病患者，以避免进展为终末期肾病。然而,用于创建此分类的标准没有考虑与肾脏组织学和肾小球滤过率测量相关的一些重要方面，导致可能高估或低估了真正确定的肾损伤。在这个小型审查中，我们将总结CKD分类中最相关的缺点，这可能会在日常临床实践中产生误导性诊断。
