Abstract：
Intraoperative study of blood flow in the brain vessels is among the most critical topics of modern neurosurgery. One of the promising methods for intraoperative monitoring of blood flow is laser speckle contrast imaging (LSCI). This systematic review aims to analyze the experience of using intraoperative LSCI in neurosurgical interventions.
The literature search was carried out in the PubMed and Web of Science databases using the keywords \"Laser-Speckle,\" \"Laser Speckle,\" \"Laser speckle contrast imaging,\" and \"LSCI.\" We allowed the search to include the following criteria: 1) publication in the English language, 2) full access to the article, 3) information about the method of treatment, and 4) the results presented for at least one patient.
The initial search resulted in the detection of 508 publications, of which 476 were eliminated during the initial assessment of titles and abstracts. Two more articles were excluded due to the lack of data in the English language. Twenty articles were found to be focused on nonhuman studies and therefore were excluded. In three more studies treatment of non-neurosurgical patients was reported. The final analysis included 8 articles with 102 patients overall.
LSCI is a promising intraoperative method for intraoperative cerebral blood flow assessing. This method offers several advantages over other modalities. The experience of use is limited to a small number of case series. Further investigation of the method and its implementation in clinical practice is needed.
The literature search was carried out in the PubMed and Web of Science databases using the keywords \"Laser-Speckle,\" \"Laser Speckle,\" \"Laser speckle contrast imaging,\" and \"LSCI.\" We allowed the search to include the following criteria: 1) publication in the English language, 2) full access to the article, 3) information about the method of treatment, and 4) the results presented for at least one patient.
The initial search resulted in the detection of 508 publications, of which 476 were eliminated during the initial assessment of titles and abstracts. Two more articles were excluded due to the lack of data in the English language. Twenty articles were found to be focused on nonhuman studies and therefore were excluded. In three more studies treatment of non-neurosurgical patients was reported. The final analysis included 8 articles with 102 patients overall.
LSCI is a promising intraoperative method for intraoperative cerebral blood flow assessing. This method offers several advantages over other modalities. The experience of use is limited to a small number of case series. Further investigation of the method and its implementation in clinical practice is needed.
摘要：
背景：术中脑血管血流的研究是现代神经外科最关键的课题之一。术中监测血流的有希望的方法之一是激光散斑对比成像（LSCI）。本系统综述旨在分析在神经外科干预中使用术中LSCI的经验。
方法：在PubMed和WebofScience数据库中使用关键词“激光斑点，\"\"激光散斑,\"\"激光散斑对比成像,\"和\"LSCI。\“我们允许搜索包括以下标准：1）以英语发布，2）完全访问文章，3）有关治疗方法的信息，和4)对至少一名患者呈现的结果。
结果：最初的搜索结果发现了508种出版物，其中476人在职称和摘要的初步评审中被淘汰。由于缺乏英语数据，另外两篇文章被排除在外。发现有20篇文章专注于非人类研究，因此被排除在外。在另外三项研究中，报道了对非神经外科患者的治疗。最终分析包括8篇文章，总共102名患者。
结论：LSCI是一种有前景的术中脑血流评估方法。这种方法提供了优于其他模式的几个优点。使用经验仅限于少数案例系列。需要进一步研究该方法及其在临床实践中的实施。
方法：在PubMed和WebofScience数据库中使用关键词“激光斑点，\"\"激光散斑,\"\"激光散斑对比成像,\"和\"LSCI。\“我们允许搜索包括以下标准：1）以英语发布，2）完全访问文章，3）有关治疗方法的信息，和4)对至少一名患者呈现的结果。
结果：最初的搜索结果发现了508种出版物，其中476人在职称和摘要的初步评审中被淘汰。由于缺乏英语数据，另外两篇文章被排除在外。发现有20篇文章专注于非人类研究，因此被排除在外。在另外三项研究中，报道了对非神经外科患者的治疗。最终分析包括8篇文章，总共102名患者。
结论：LSCI是一种有前景的术中脑血流评估方法。这种方法提供了优于其他模式的几个优点。使用经验仅限于少数案例系列。需要进一步研究该方法及其在临床实践中的实施。
