PDF(Pubmed)
Abstract：
UNASSIGNED: Zoster-associated pain (ZAP) is notoriously difficult to treat. Pulsed radiofrequency (PRF) and short-term nerve electrical stimulation (st-NES) have been proven effective treatments for ZAP. However, it is still unclear which technique provides improved analgesia in ZAP. This study is based on a large-scale, long-term follow-up to evaluate the efficacy and safety between st-NES and PRF.
UNASSIGNED: All eligible ZAP patients treated with st-NES or PRF in our department were enrolled. Cohorts were divided into the st-NES group and the PRF group. A 1:1 ratio propensity score matching (PSM) was used to balance the baseline characteristics. The PS-matched cohort was adopted to investigate the efficacy and safety of the two treatments. The ordinal regression analysis was performed to determine the variables affecting the treatment effect of ZAP.
UNASSIGNED: A total of 226 patients were included after PSM. The numerical rating scale (NRS) scores in st-NES and PRF groups considerably reduced compared to baseline levels after treatment. The NRS scores in the st-NES group were obviously lower than those in the PRF group at discharge, 1, 3, 6, 12, and 24 months. During the follow-up period, the NRS reduction rate remained higher in the st-NES group than in the PRF group (P < 0.01). The dosage of medication, Pittsburgh Sleep Quality Index (PSQI) score, and the number of patients with aggravated pain after discharge in the st-NES group were significantly less than in the PRF group after treatment.
UNASSIGNED: Short-term nerve electrical stimulation has been shown to be more advantageous than PRF for pain relief and quality of life improvement for ZAP patients.
UNASSIGNED: All eligible ZAP patients treated with st-NES or PRF in our department were enrolled. Cohorts were divided into the st-NES group and the PRF group. A 1:1 ratio propensity score matching (PSM) was used to balance the baseline characteristics. The PS-matched cohort was adopted to investigate the efficacy and safety of the two treatments. The ordinal regression analysis was performed to determine the variables affecting the treatment effect of ZAP.
UNASSIGNED: A total of 226 patients were included after PSM. The numerical rating scale (NRS) scores in st-NES and PRF groups considerably reduced compared to baseline levels after treatment. The NRS scores in the st-NES group were obviously lower than those in the PRF group at discharge, 1, 3, 6, 12, and 24 months. During the follow-up period, the NRS reduction rate remained higher in the st-NES group than in the PRF group (P < 0.01). The dosage of medication, Pittsburgh Sleep Quality Index (PSQI) score, and the number of patients with aggravated pain after discharge in the st-NES group were significantly less than in the PRF group after treatment.
UNASSIGNED: Short-term nerve electrical stimulation has been shown to be more advantageous than PRF for pain relief and quality of life improvement for ZAP patients.
摘要：
未经证实：带状疱疹相关性疼痛（ZAP）是出了名的难以治疗。脉冲射频（PRF）和短期神经电刺激（st-NES）已被证明是ZAP的有效治疗方法。然而,尚不清楚哪种技术可改善ZAP的镇痛效果。这项研究是基于大规模的，长期随访以评估st-NES和PRF之间的有效性和安全性。
UNASSIGNED：纳入所有在我们科室接受st-NES或PRF治疗的合格ZAP患者。队列分为st-NES组和PRF组。使用1:1比率倾向评分匹配(PSM)来平衡基线特征。采用PS匹配的队列研究两种治疗方法的疗效和安全性。进行有序回归分析以确定影响ZAP治疗效果的变量。
未经批准：共纳入226例PSM后患者。与治疗后的基线水平相比，st-NES和PRF组的数字评定量表（NRS）评分显着降低。出院时,st-NES组的NRS评分明显低于PRF组,1、3、6、12和24个月。在后续期间,St-NES组NRS降低率高于PRF组(P<0.01)。药物的剂量，匹兹堡睡眠质量指数（PSQI）评分，治疗后,st-NES组患者出院后疼痛加重例数明显少于PRF组。
UNASSIGNED：已证明短期神经电刺激比PRF更有利于ZAP患者的疼痛缓解和生活质量改善。
UNASSIGNED：纳入所有在我们科室接受st-NES或PRF治疗的合格ZAP患者。队列分为st-NES组和PRF组。使用1:1比率倾向评分匹配(PSM)来平衡基线特征。采用PS匹配的队列研究两种治疗方法的疗效和安全性。进行有序回归分析以确定影响ZAP治疗效果的变量。
未经批准：共纳入226例PSM后患者。与治疗后的基线水平相比，st-NES和PRF组的数字评定量表（NRS）评分显着降低。出院时,st-NES组的NRS评分明显低于PRF组,1、3、6、12和24个月。在后续期间,St-NES组NRS降低率高于PRF组(P<0.01)。药物的剂量，匹兹堡睡眠质量指数（PSQI）评分，治疗后,st-NES组患者出院后疼痛加重例数明显少于PRF组。
UNASSIGNED：已证明短期神经电刺激比PRF更有利于ZAP患者的疼痛缓解和生活质量改善。
