PDF(Pubmed)
Abstract：
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently described CNS inflammatory disorder that may manifest with optic neuritis, myelitis, seizures, and/or acute disseminated encephalomyelitis. While MOG-specific antibodies in patients with MOGAD are IgG1, a T-cell-dependent antibody isotype, immunologic mechanisms of this disease are not fully understood. Thymic hyperplasia can be associated with certain autoimmune diseases. In this report we describe a case of MOGAD associated with thymic hyperplasia in a young adult.
摘要：
髓磷脂少突胶质细胞糖蛋白抗体相关疾病（MOGAD）是最近描述的中枢神经系统炎症性疾病，可能表现为视神经炎，脊髓炎,癫痫发作,和/或急性播散性脑脊髓炎。虽然MOGAD患者的MOG特异性抗体是IgG1，一种T细胞依赖性抗体同种型，这种疾病的免疫机制尚未完全了解。胸腺增生可能与某些自身免疫性疾病有关。在本报告中，我们描述了一个年轻人中与胸腺增生相关的MOGAD病例。
