OBJECTIVE: To estimate the prevalence of a men\'s health history associated with MBC as well as the anthropometric and clinical characteristics of the study population.
METHODS: This cross-sectional study included all men according to original biological sex over 18 years of age with a history of breast cancer who sought care at the Hospital Italiano de Buenos Aires [Italian Hospital of Buenos Aires] between January 2010 and December 2018.
RESULTS: We included 57 men with breast cancer. Their median age was 71 years. Of them, 53.06% had obesity and 24.53% had diabetes. With respect to men\'s health history, 5.56% (2/36) had infertility, 29.17% (14/48) had gynaecomastia and 60.71% (17/28) had sexual dysfunction. Some 63% (7/11) had androgen deficiency based on laboratory diagnosis; of them, 45.45% (5/11) had high gonadotropins.
CONCLUSIONS: We identified similarities with the literature as to the prevalence of obesity, diabetes and infertility in patients with MBC. The prevalence of testosterone deficiency was higher than reported for men of the same age. Many of these factors support the need to examine the role of endogenous hormones. Further research is required to help physicians care for and counsel men at higher risk of this disease.
目的:评估男性健康史与MBC相关的患病率以及研究人群的人体测量和临床特征。
方法:这项横断面研究包括所有18岁以上有乳腺癌病史的男性,这些男性在2010年1月至2018年12月期间在意大利布宜诺斯艾利斯医院[布宜诺斯艾利斯意大利医院]寻求治疗。
结果:我们纳入了57名患有乳腺癌的男性。他们的平均年龄为71岁。其中,53.06%患有肥胖症,24.53%患有糖尿病。关于男性的健康史,5.56%(2/36)有不孕症,29.17%(14/48)有妇科乳房发育,60.71%(17/28)有性功能障碍。根据实验室诊断,约63%(7/11)患有雄激素缺乏症;其中,45.45%(5/11)有高促性腺激素。
结论:我们发现了肥胖患病率与文献的相似性,MBC患者的糖尿病和不孕症。睾酮缺乏的患病率高于同龄男性的报告。这些因素中的许多都支持需要检查内源性激素的作用。需要进一步的研究来帮助医生护理和咨询这种疾病风险较高的男性。