PDF(Pubmed)
Abstract：
Obesity is a global epidemic with steadily increasing prevalence in most countries. Weight loss is generally challenging for patients to tackle in the face of the temptation to overeat and avoid physical activity. Hence, clinicians and patients alike are likely to steer toward the use of anorexigens. We report the case of a 33-year-old female with no significant cardiac history who presented with dyspnea, productive cough, and chest pressure for one month and was diagnosed with new-onset heart failure with a reduced ejection fraction secondary to prolonged phentermine use. The authors aim to highlight phentermine\'s potential for precipitating heart failure, even in a young, relatively healthy person, especially with a growing obese population. Ultimately, healthy weight loss can be achieved by implementing dietary changes and encouraging adequate physical activity, as the World Health Organization (WHO) recommended. Anorectic drugs may be employed for short-term use. Further research concerning the long-term side effects of phentermine may avert the prescriber and patient from abusing this drug.
摘要：
肥胖是一种全球流行病，在大多数国家患病率稳步上升。面对暴饮暴食和避免身体活动的诱惑，减肥对于患者来说通常是具有挑战性的。因此，临床医生和患者都可能转向使用厌食症。我们报告了一个33岁的女性，没有明显的心脏病史，出现呼吸困难，生产性咳嗽,和胸压持续1个月，被诊断为新发心力衰竭，长期使用苯丁胺后射血分数降低。作者旨在强调芬特明诱发心力衰竭的潜力，即使在一个年轻的，相对健康的人，尤其是在肥胖人口不断增长的情况下。最终,健康的减肥可以通过实施饮食改变和鼓励足够的身体活动来实现，正如世界卫生组织（WHO）所建议的那样。厌食药物可用于短期使用。关于芬特明长期副作用的进一步研究可能会避免处方者和患者滥用该药物。
