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Abstract：
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that represents a prodigious challenge of diagnosis and treatment. In 2019, under the leadership of the Chinese Rheumatology Association, a multidisciplinary guideline development group was established to develop an evidence-based diagnosis and treatment guideline for patients with SLE in PR China. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to evaluate the quality of evidence and the strength of recommendations. The guideline was reported following the Reporting Items for Practice Guidelines in Healthcare (RIGHT) checklist. In this guideline, we provided recommendations for SLE classification criteria, disease activity monitoring and assessment, medication administration and considerations for SLE patients with organs and systems involved, and management of special populations such as SLE patients in the setting of pregnancy. This guideline serves as an evidence-based tool for Chinese clinicians to diagnose and treat patients with SLE.
摘要：
系统性红斑狼疮（SLE）是一种异质性自身免疫性疾病，对诊断和治疗提出了巨大挑战。2019年，在中华风湿病学会的领导下，我们成立了一个多学科指南制定小组,为中国的SLE患者制定循证诊断和治疗指南.建议评估的分级，使用开发和评估（GRADE）方法来评估证据的质量和建议的强度。该指南是根据医疗保健实践指南（RIGHT）清单的报告项目报告的。在本准则中,我们提供了SLE分类标准的建议，疾病活动监测和评估，涉及器官和系统的SLE患者的药物管理和注意事项，和特殊人群的管理，如SLE患者在怀孕的设置。本指南作为中国临床医生诊断和治疗SLE患者的循证工具。
