关键词: Allergic rhinitis Bronchial asthma Nasobronchial reflex Pulmonary function test Spirometry United airway disease

来  源:   DOI:10.1007/s12070-021-02785-5   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Allergic rhinitis, beginning from childhood, is a global health problem. According to the literature, allergic rhinitis has been found association with asthma and other allergic manifestations. In this study we like to find out the significance and prognostic importance of spirometry in allergic rhinitis. The study was carried out over a period of 2 years, with 63 cases and controls each. Subjects in the age of 20-55 years with allergic rhinitis and SFAR score of > / = 7 were included as a case. Participants were interviewed and sent for spirometry. Controls were recruited from the retrospective data of healthy individuals with spirometry parameters done for health checkup. These controls had an SFAR score of < 7. All the data obtained were analyzed and compared between cases and controls. The mean age of the cases and controls were 33.17 ± 10.817 and 44.41 ± 7.4, respectively. Majority of cases and controls were males (60.3% and 57.1%). A statistically significant difference in FEF25-75% among cases and controls was noted (p = 0.00), thus proving probability of developing small airway obstruction in subjects with allergic rhinitis. Subjects with allergic rhinitis have a probability of developing small airway obstruction with subclinical changes, hence necessitating the need of regular follow-up.
摘要:
过敏性鼻炎,从童年开始,是一个全球性的健康问题。根据文献,已发现过敏性鼻炎与哮喘和其他过敏性表现有关。在这项研究中,我们希望找出肺活量测定在过敏性鼻炎中的意义和预后重要性。这项研究进行了两年,各63例,对照。包括年龄在20-55岁的过敏性鼻炎和SFAR评分>/=7的受试者作为病例。参与者接受了采访并接受了肺活量测定。从健康个体的回顾性数据中招募对照,并使用肺活量测定参数进行健康检查。这些对照具有<7的SFAR评分。对获得的所有数据进行分析,并在病例和对照之间进行比较。病例和对照组的平均年龄分别为33.17±10.817和44.41±7.4。大多数病例和对照组为男性(60.3%和57.1%)。病例和对照组之间的FEF25-75%有统计学意义的差异(p=0.00),从而证明过敏性鼻炎患者发生小气道阻塞的可能性。患有过敏性鼻炎的受试者有可能发生亚临床改变的小气道阻塞,因此需要定期跟进。
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