Abstract：
Lignan is a class of diphenolic compounds that arise from the condensation of two phenylpropanoid moieties. Oilseed and cereal crops (e.g., flaxseed, sesame seed, wheat, barley, oats, rye, etc.) are major sources of plant lignan. Methods for commercial isolation of the lignan secoisolariciresinol diglucoside (SDG) are not well reported, as most publications describing the detection, extraction, and enrichment of SDG use methods that have not been optimized for commercial scale lignan recovery. Simply scaling up laboratory methods would require expensive infrastructure to achieve a marketable yield and reproducible product quality. Therefore, establishing standard protocols to produce SDG and its derivatives on an industrial scale is critical to decrease lignan cost and increase market opportunities. This review summarizes the human health benefits of flaxseed lignan consumption, lignan physicochemical properties, and mammalian lignan metabolism, and describes methods for detecting, extracting, and enriching flaxseed lignan. Refining and optimization of these methods could lead to the development of inexpensive lignan sources for application as an ingredient in medicines, dietary supplements, and other healthy ingredients.
摘要：
木质素是一类由两个类苯丙素部分缩合产生的二酚化合物。油料作物和谷类作物(例如，亚麻籽，芝麻,小麦,大麦,燕麦,黑麦,等。)是植物木脂素的主要来源。商业分离木脂素类Secoisoliciresinol二葡糖苷（SDG）的方法没有很好的报道，作为描述检测的大多数出版物，提取,和富集SDG使用方法尚未优化商业规模木酚素回收。简单地扩大实验室方法将需要昂贵的基础设施来实现可销售的产量和可重复的产品质量。因此,建立以工业规模生产SDG及其衍生物的标准协议对于降低木酚素成本和增加市场机会至关重要。这篇综述总结了亚麻籽木酚素消费对人类健康的益处，木酚素理化性质，和哺乳动物木酚素代谢，并描述了检测方法，提取,丰富亚麻籽木酚素。这些方法的改进和优化可以导致开发廉价的木酚素来源，用作药物成分，膳食补充剂，和其他健康成分。
