Abstract：
Novel multifunctional ZnO:Gd@ZIF-8 hybrid inorganic-organic nanocomposites with tunable luminescent-magnetic performance were successfully fabricated using wet chemistry synthesis routes. Physico-chemical characterization including crystal structure, phase compositions, morphology, surface properties, as well as photoluminescent and magnetic characteristics was performed using powder X-ray diffraction (XRD), FT-IR analysis, transmission and scanning electron microscopies (TEM/SEM), N2 adsorption/desorption, SQUID magnetometer, and photoluminescence spectroscopy. The biological studies of obtained materials, such as cytotoxicity profile and in vitro MRI imaging also investigated for potential use as contrast agents. Results showed that the doping with Gd3+ in a broad concentration range and the presence of ZIF-8 layer on ZnO affect the physico-chemical properties of the obtained composites. The obtained porous ZnO:Gd@ZIF-8 composites were highly crystalline with a large surface area. The XRD study indicated the formation of hexagonal wurtzite structure for ZnO and ZnO:Gd3+ (1-5 at.%). Luminescent studies showed, that ZnO is an ideal matrix for the incorporation of Gd3+ ions in a broad concentration range with efficient green luminescence. The PL intensity reached the maximum up to 5 at.% of Gd3+. The zeta potential values indicated the good stability of obtained nanoparticles. Proposed new materials with paramagnetic behavior and outstanding MR imaging capability could be used as potential contrast agents for magnetic resonance imaging.
摘要：
使用湿化学合成路线成功制备了具有可调发光磁性能的新型多功能ZnO：Gd@ZIF-8杂化无机-有机纳米复合材料。物理化学表征，包括晶体结构，相组成，形态学,表面属性,以及光致发光和磁特性进行了粉末X射线衍射（XRD），FT-IR分析,透射和扫描电子显微镜（TEM/SEM），N2吸附/解吸，SQUID磁力计,和光致发光光谱。获得的材料的生物学研究，例如细胞毒性谱和体外MRI成像也被研究作为造影剂的潜在用途。结果表明，在宽浓度范围内掺杂Gd3和ZnO上ZIF-8层的存在会影响所得复合材料的理化性能。所获得的多孔ZnO:Gd@ZIF-8复合材料是高度结晶的,具有大的表面积。XRD研究表明，ZnO和ZnO：Gd3（1-5at。%).发光研究表明,ZnO是在宽浓度范围内掺入Gd3离子并具有有效绿色发光的理想基质。PL强度达到最大，达5at。%的Gd3+。ζ电位值表明所获得的纳米颗粒具有良好的稳定性。提出的具有顺磁行为和出色MR成像能力的新材料可用作磁共振成像的潜在造影剂。
