关键词: animal testing non-traumatic tracheal stent removal technique pediatrics removable stent tracheomalacia

来  源:   DOI:10.3390/jcm11226757

Abstract:
BACKGROUND: Congenital tracheomalacia is a pathology with no consensus of medical or surgical approach. The permanent nature and the major complications associated with metallic stents have limited their use over the years. The purpose of this study was to evaluate the feasibility of a helical stent design removal.
METHODS: Ten dogs diagnosed with tracheal collapse and treated with the helical stent were involved in the study. Animals were classified into three groups depending on stent indwelling time. Prior to the removal, endoscopic evaluation was performed to assess endothelization grade, mucous accumulation, and the presence of stenosis. During the removal, bleeding, fracture, or impossibility of removal were noted. After the removal, all macroscopic mucosal changes were recorded.
RESULTS: Technical success was 100%, without any complications. Complete epithelization of the stent was visualized in 7/10 animals. The removal procedure duration ranged from 2-12 min. At post-removal endoscopy, bleeding or epithelial damage, was visualized in any case. Stent fracture during removal occurred in one animal.
CONCLUSIONS: The removal of a metallic stent with spiral geometry is feasible, simple, and without complications, regardless of the degree of neo-epithelialization.
摘要:
背景:先天性气管软化是一种没有医学或手术方法共识的病理。多年来,金属支架的永久性和主要并发症限制了它们的使用。这项研究的目的是评估螺旋支架设计移除的可行性。
方法:本研究涉及10只诊断为气管塌陷并接受螺旋支架治疗的狗。根据支架留置时间将动物分为三组。在移除之前,进行内镜评估以评估内皮化分级,粘液积聚,和狭窄的存在。在移除过程中,出血,骨折,或不可能删除被注意到。移除后,记录所有肉眼可见的粘膜变化.
结果:技术成功100%,没有任何并发症。在7/10的动物中观察到支架的完全上皮化。移除程序持续时间为2-12分钟。在取出后的内窥镜检查中,出血或上皮损伤,在任何情况下都是可视化的。一只动物在取出期间发生支架骨折。
结论:去除具有螺旋几何形状的金属支架是可行的,简单,并且没有并发症,不管新上皮化的程度。
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