Abstract:
Described in the seminal paper by Hans Chiari in 1891, the Chiari I malformation (CMI) is a radiographic diagnosis commonly encountered by neurosurgeons and is often treated surgically with generally positive clinic outcomes. Studies have documented that 1% to 4% of patients undergoing MRI of the brain or cervical spine will be diagnosed with CMI, characterized by greater than 5 mm tonsillar herniation below the foramen magnum. More recently CMI has been described as a spectrum of disease, which includes Chiari 0, Chiari 1.5, and the complex Chiari. Primarily through multicenter clinical outcomes research, our understanding of the pathology continues to evolve.
摘要:
在HansChiari于1891年发表的开创性论文中,ChiariI畸形(CMI)是神经外科医生通常会遇到的放射学诊断,通常通过手术治疗,临床结果通常是积极的。研究表明,接受脑部或颈椎MRI的患者中有1%至4%将被诊断为CMI,特征是在大孔下面大于5毫米的扁桃体突出。最近,CMI被描述为一种疾病谱,其中包括Chiari0,Chiari1.5和复杂的Chiari。主要通过多中心临床结果研究,我们对病理学的理解在不断发展。