%0 Journal Article
%T Craniovertebral Junction Instability in the Setting of Chiari Malformation.
%A Dastagirzada YM
%A Kurland DB
%A Hankinson TC
%A Anderson RC
%J Neurosurg Clin N Am
%V 34
%N 1
%D Jan 2023
%M 36424053
%F 3.348
%R 10.1016/j.nec.2022.09.006
%X Described in the seminal paper by Hans Chiari in 1891, the Chiari I malformation (CMI) is a radiographic diagnosis commonly encountered by neurosurgeons and is often treated surgically with generally positive clinic outcomes. Studies have documented that 1% to 4% of patients undergoing MRI of the brain or cervical spine will be diagnosed with CMI, characterized by greater than 5 mm tonsillar herniation below the foramen magnum. More recently CMI has been described as a spectrum of disease, which includes Chiari 0, Chiari 1.5, and the complex Chiari. Primarily through multicenter clinical outcomes research, our understanding of the pathology continues to evolve.