Abstract：
BACKGROUND: Vestibular Schwannomas are benign tumors arising from the VIII CN. Surgical treatment is indicated in case of tumors larger than 2.5 cm in the cerebellopontine angle or in the case of cranial nerve dysfunction. The aim of the present study was to evaluate the QoL by means of the PANQOL questionnaire in a group of surgically treated patients mainly affected by large and giant VS Methods: All patients underwent preoperative and postoperative otoneurological evaluation and gadolinium enhanced MRI and they completed, independently, the PANQOL questionnaire at last follow up.
RESULTS: 70% of patients presented with large Koos III or IV VS Each domain of PANQOL showed a strong correlation with the total PANQOL score. In relation to the postoperative facial nerve function, patients with poorer function showed significantly lower score in the facial dysfunction and pain, patients with postoperative balance problems showed a significantly lower PANQOL score for domains of balance and pain.
CONCLUSIONS: This study showed that postoperative QoL of patients was acceptable even if there were some domains that were more affected, such as hearing and balance domains; therefore, the lowest scores suggest the need for vestibular rehabilitation programs and strategies that improve postoperative hearing.
RESULTS: 70% of patients presented with large Koos III or IV VS Each domain of PANQOL showed a strong correlation with the total PANQOL score. In relation to the postoperative facial nerve function, patients with poorer function showed significantly lower score in the facial dysfunction and pain, patients with postoperative balance problems showed a significantly lower PANQOL score for domains of balance and pain.
CONCLUSIONS: This study showed that postoperative QoL of patients was acceptable even if there were some domains that were more affected, such as hearing and balance domains; therefore, the lowest scores suggest the need for vestibular rehabilitation programs and strategies that improve postoperative hearing.
摘要：
背景：前庭神经鞘瘤是由VIIICN引起的良性肿瘤。在桥小脑角大于2.5cm的肿瘤或颅神经功能障碍的情况下，需要手术治疗。本研究的目的是通过PANQOL问卷评估一组主要受大型和大型VS影响的手术治疗患者的QoL。独立,最后随访的PANQOL问卷。
结果：70％的患者出现大的KoosIII或IVVSPANQOL的每个域显示与PANQOL总评分有很强的相关性。关于术后面神经功能，功能较差的患者在面部功能障碍和疼痛方面得分明显较低，有术后平衡问题的患者在平衡和疼痛领域的PANQOL评分显著降低.
结论：这项研究表明，即使某些领域受影响更大，患者的术后QoL也是可以接受的，如听觉和平衡域；因此，最低评分提示需要前庭康复计划和改善术后听力的策略.
结果：70％的患者出现大的KoosIII或IVVSPANQOL的每个域显示与PANQOL总评分有很强的相关性。关于术后面神经功能，功能较差的患者在面部功能障碍和疼痛方面得分明显较低，有术后平衡问题的患者在平衡和疼痛领域的PANQOL评分显著降低.
结论：这项研究表明，即使某些领域受影响更大，患者的术后QoL也是可以接受的，如听觉和平衡域；因此，最低评分提示需要前庭康复计划和改善术后听力的策略.
