从结构到功能 - 髓样 C 型凝集素受体的配体识别。
关键词: BCG, Bacillus Calmette-Guérin C-type lectin receptors CLR, C-type lectin receptor CRD, Carbohydrate recognition domain CTL, C-type lectin CTLD, C-type lectin-like domain DAMP, Danger-associated molecular pattern DAP12, DNAX-activation protein 12 DC, Dendritic cell DC-SIGN, Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin DCAR, Dendritic cell immunoactivating receptor DCIR, Dendritic cell immunoreceptor DLS, Dynamic light scattering DNGR, Dendritic cell natural killer lectin group receptor Dectin, Dendritic cell-associated C-type lectin receptor ECD, Extracellular domain ECM, Experimental cerebral malaria ELISA, Enzyme-linked-immunosorbent-assay FRET, Förster resonance energy transfer Fc, Fragment crystallizable FcRγ, Fragment crystallizable receptor γ Fuc, Fucose GTfs, Glycosyltransferases Gal, Galactose GalNAc, N-acetylgalactosamine Glc, Glucose GlcNAc, N-acetylglucosamine HIV-1, Human immunodeficiency virus 1 HLA, Human leukocyte antigen HSPC, Hematopoietic stem and progenitor cells Host-pathogen interaction IL, Interleukin ITAM, Immunoreceptor tyrosine-based activating motif ITC, Isothermal titration calorimetry ITIM, Immunoreceptor tyrosine-based inhibitory motif Ig, Immunoglobulin Immune modulation LPS, Lipopolysaccharide Lac, Lactose (Gal-β1,4-Glc) LacNAc, N-acetyllactosamine (Gal-β1,4-GlcNAc) Le, Lewis Ligand identification MBP, Mannan-binding protein MCL, Macrophage C-type lectin MD, Molecular dynamics MDL, Myeloid DAP12-associating lectin MGDG, Monoglucosyldiacylglycerol MGL, Macrophage galactose-type lectin MHC, Major histocompatibility complex MICL, Myeloid inhibitory C type-like lectin MMR, Macrophage mannose receptor MSU, Monosodium urate Man, Mannose Mincle, Macrophage inducible Ca2+-dependent lectin receptor Mφ, Macrophages NF-κB, Nuclear factor kappa B NFAT, Nuclear factor of activated T-cells NK, Natural killer (cells) NMR, Nuclear magnet resonance PAMP, Pathogen-associated molecular pattern PDPN, Podoplanin PRR, Pattern recognition receptor QCM, Quartz crystal microbalance RIA, Radioimmunoassays ROS, Reactive oxygen species Raf-1, Rapidly accelerated fibrosarcoma 1 SAMP, Self-associated molecular pattern SAP130, Spliceosome-associated protein 130 SARS-CoV, SARS coronavirus SH2, Src-homology 2 SHP, Src homology region 2 domain-containing phosphatase SIGNR, Specific intracellular adhesion molecule-3 grabbing non-integrin homolog-related SPR, Surface plasmon resonance SYK, Spleen tyrosine kinase Self-non-self-discrimination Signaling flexibility TCA, Tricarboxylic acid TDM, Trehalose-6,6′-dimycolate TLC, Thin-layer chromatography TLR, Toll-like receptor TNF, Tumor necrosis factor WTA, Wall teichoic acid mTOR, Mammalian target of rapamycin
来 源:
DOI:10.1016/j.csbj.2022.10.019
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