Abstract：
The aim of the study was to examine the applicability of bioactive and antibacterial nanoparticles to an experimental adhesive. The adhesive (60 wt% BisGMA, 15 wt% TEGDMA, 25 wt% HEMA) was mixed with combinations of 5 wt% methacryl-functionalized polyhedral oligomeric silsesquioxane (MA-POSS) and one kind of bioactive/antibacterial nanoparticles: 1 wt% core-shell silica-silver nanoparticle (SiO2@Ag), 1 wt% bioactive glass with bismuth (BAG-Bi) or 1 wt% calcium phosphate (CAP). Pure adhesive served as control. The physicochemical (degree of conversion (DC), linear shrinkage (LS), shear and complex viscosity, water sorption (WS), sol fraction (SF)), biological (antimicrobial effect) and bioactive (mineral precipitation) properties were investigated. DC and LS remained unchanged. The combination of BAG-Bi/MA-POSS resulted in a significantly increased WS and SF compared to control. In addition, the combination of CAP/MA-POSS slightly increased the shear viscosity of the adhesive. The addition of the nanoparticles did not influence the antimicrobial effects compared to the pure adhesive. Improved mineral inducing capacity could be detected in all nanoparticle combinations. The combination of bioactive and/or antibacterial nanoparticles showed improved mineral inducing capacity, but no antibacterial properties. The material properties were not or only slightly affected.
摘要：
该研究的目的是检查生物活性和抗菌纳米颗粒对实验粘合剂的适用性。粘合剂(60重量%BisGMA，15wt%TEGDMA，25wt％的HEMA）与5wt％的甲基丙烯酰基官能化的多面体低聚倍半硅氧烷（MA-POSS）和一种生物活性/抗菌纳米颗粒的组合混合：1wt％的核-壳二氧化硅-银纳米颗粒（SiO2@Ag），1重量%的生物活性玻璃与铋(BAG-Bi)或1重量%的磷酸钙(CAP)。纯粘合剂用作对照。物理化学(转化度(DC)，线性收缩(LS)，剪切和复数粘度，吸水率（WS），溶胶分数（SF）），生物（抗菌作用）和生物活性（矿物质沉淀）特性进行了研究。DC和LS保持不变。与对照相比,BAG-Bi/MA-POSS的组合导致显著增加的WS和SF。此外,CAP/MA-POSS的组合略微增加了粘合剂的剪切粘度。与纯粘合剂相比,纳米颗粒的添加不影响抗微生物效果。在所有纳米颗粒组合中都可以检测到改善的矿物质诱导能力。生物活性和/或抗菌纳米颗粒的组合显示出改善的矿物质诱导能力，但没有抗菌性能。材料性能没有受到影响或仅受到轻微影响。
