PDF(Pubmed)
Abstract：
OBJECTIVE: To determine the effects of dietary sugar or carbohydrate restriction on physical activity energy expenditure, energy intake, and physiological outcomes across 24 h.
METHODS: In a randomized, open-label crossover design, twenty-five healthy men (n = 10) and women (n = 15) consumed three diets over a 24-h period: moderate carbohydrate and sugar content (MODSUG = 50% carbohydrate [20% sugars], 15% protein, 35% fat); low sugar content (LOWSUG = 50% carbohydrate [< 5% sugars], 15% protein, 35% fat); and low carbohydrate content (LOWCHO = 8% carbohydrate [< 5% sugars], 15% protein, 77% fat). Postprandial metabolic responses to a prescribed breakfast (20% EI) were monitored under laboratory conditions before an ad libitum test lunch, with subsequent diet and physical activity monitoring under free-living conditions until blood sample collection the following morning.
RESULTS: The MODSUG, LOWSUG and LOWCHO diets resulted in similar mean [95%CI] rates of both physical activity energy expenditure (771 [624, 919] vs. 677 [565, 789] vs. 802 [614, 991] kcal·d-1; p = 0.29] and energy intake (2071 [1794, 2347] vs. 2195 [1918, 2473] vs. 2194 [1890, 2498] kcal·d-1; P = 0.34), respectively. The LOWCHO condition elicited the lowest glycaemic and insulinaemic responses to breakfast (P < 0.01) but the highest 24-h increase in LDL-cholesterol concentrations (P < 0.001), with no differences between the MODSUG and LOWSUG treatments. Leptin concentrations decreased over 24-h of consuming LOWCHO relative to LOWSUG (p < 0.01).
CONCLUSIONS: When energy density is controlled for, restricting either sugar or total dietary carbohydrate does not modulate physical activity level or energy intake over a 24-h period (~ 19-h free-living) despite substantial metabolic changes.
UNASSIGNED: NCT03509610, https://clinicaltrials.gov/show/NCT03509610.
METHODS: In a randomized, open-label crossover design, twenty-five healthy men (n = 10) and women (n = 15) consumed three diets over a 24-h period: moderate carbohydrate and sugar content (MODSUG = 50% carbohydrate [20% sugars], 15% protein, 35% fat); low sugar content (LOWSUG = 50% carbohydrate [< 5% sugars], 15% protein, 35% fat); and low carbohydrate content (LOWCHO = 8% carbohydrate [< 5% sugars], 15% protein, 77% fat). Postprandial metabolic responses to a prescribed breakfast (20% EI) were monitored under laboratory conditions before an ad libitum test lunch, with subsequent diet and physical activity monitoring under free-living conditions until blood sample collection the following morning.
RESULTS: The MODSUG, LOWSUG and LOWCHO diets resulted in similar mean [95%CI] rates of both physical activity energy expenditure (771 [624, 919] vs. 677 [565, 789] vs. 802 [614, 991] kcal·d-1; p = 0.29] and energy intake (2071 [1794, 2347] vs. 2195 [1918, 2473] vs. 2194 [1890, 2498] kcal·d-1; P = 0.34), respectively. The LOWCHO condition elicited the lowest glycaemic and insulinaemic responses to breakfast (P < 0.01) but the highest 24-h increase in LDL-cholesterol concentrations (P < 0.001), with no differences between the MODSUG and LOWSUG treatments. Leptin concentrations decreased over 24-h of consuming LOWCHO relative to LOWSUG (p < 0.01).
CONCLUSIONS: When energy density is controlled for, restricting either sugar or total dietary carbohydrate does not modulate physical activity level or energy intake over a 24-h period (~ 19-h free-living) despite substantial metabolic changes.
UNASSIGNED: NCT03509610, https://clinicaltrials.gov/show/NCT03509610.
摘要：
目的：为了确定饮食中糖或碳水化合物限制对身体活动能量消耗的影响，能量摄入，和24小时的生理结果。
方法：在随机分组中，开放标签交叉设计，25名健康男性（n=10）和女性（n=15）在24小时内食用三种饮食：适度的碳水化合物和糖含量（MODSUG=50％碳水化合物[20％糖]，15%蛋白质，35％脂肪）；低糖含量（LOWSUG=50％碳水化合物[<5％糖]，15%蛋白质，35％脂肪）；和低碳水化合物含量（LOWCHO=8％碳水化合物[<5％糖]，15%蛋白质，77％的脂肪）。在随意测试午餐之前，在实验室条件下监测餐后对规定早餐（20％EI）的代谢反应，随后在自由生活条件下进行饮食和身体活动监测，直到第二天早上收集血液样本。
结果：MODSUG，LOWSUG和LOWCHO饮食导致两种身体活动能量消耗的平均[95CI]率相似（771[624，919]与677[565,789]vs.802[614，991]kcal·d-1；p=0.29]和能量摄入（2071[1794，2347]与2195[1918,2473]vs.2194[1890,2498]千卡·d-1；P=0.34)，分别。LOWCHO条件引起最低的血糖和胰岛素对早餐的反应（P<0.01），但最高的24小时LDL-胆固醇浓度增加（P<0.001），MODSUG和LOWSUG治疗之间没有差异。瘦素浓度在消耗LOWCHO的24小时内相对于LOWSUG降低(p<0.01)。
结论：当能量密度被控制时，尽管代谢发生了实质性变化，但限制糖或总饮食碳水化合物并不能调节24小时（〜19小时自由生活）的身体活动水平或能量摄入。
UNASSIGNED：NCT03509610，https://clinicaltrials.gov/show/NCT03509610。
方法：在随机分组中，
结果：MODSUG，
结论：当能量密度被控制时，
UNASSIGNED：NCT03509610，https://clinicaltrials.gov/show/NCT03509610。
