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Abstract：
Yellow nail syndrome (YNS) is a rare disorder initially described in 1964. It is characterized by a classical triad: yellow nails, lymphedema, and respiratory manifestations. We present a 71-year-old woman who presented with progressive dyspnea. Medical history includes hypertension treated with amlodipine. Examination showed bilateral lower extremity non-pitting edema, yellowish discoloration of nails, and bilateral pleural effusion. Thoracentesis demonstrated chylous effusion. The presumptive diagnosis was YNS. Assuming amlodipine as a cause of interstitial edema, it was stopped, and the symptoms improved gradually. After two months, amlodipine was restarted externally, and the dyspnea relapsed. Amlodipine was discontinued again. After two years of amlodipine cessation, the patient remained well without symptoms. The progression and resolution of symptoms point to amlodipine as a suggested cause of YNS. Paying attention to the prescribed drugs was the key to diagnosing and resolving serious complications.
摘要：
黄指甲综合征（YNS）是一种罕见的疾病，最初于1964年描述。它的特点是经典的三合会：黄色的指甲，淋巴水肿,和呼吸道表现。我们介绍了一名71岁的女性，她表现出进行性呼吸困难。病史包括用氨氯地平治疗的高血压。检查显示双侧下肢无凹陷性水肿，指甲变黄，双侧胸腔积液。胸腔穿刺术显示乳糜积液。推定诊断为YNS。假设氨氯地平是间质性水肿的原因，它被阻止了,症状逐渐好转。两个月后,氨氯地平从外部重新启动，呼吸困难复发。再次停用氨氯地平。停用氨氯地平两年后,患者病情良好，无症状。症状的进展和消退表明氨氯地平是YNS的建议原因。注意处方药物是诊断和解决严重并发症的关键。
