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Abstract：
A 67-year-old man with a history of IgM deficiency and pulmonary fibrosis and bronchiectasis was admitted for management of worsening symptoms. Investigations revealed exudative pleural effusion with rapidly progressive bronchiectasis. Although a potential trigger of bronchiectasis and pulmonary fibrosis was not identified despite extensive work-up by several physicians in the past, a bedside observation of yellow dystrophic nails on all extremities revealed the diagnosis. This case report helps to remind clinicians of a rare medical disorder of still uncertain aetiology and no available cure. This case is consistent with a few previous case reports that suggest a potential association with selective immunoglobulin deficiency.
CONCLUSIONS: Yellow nail syndrome is a rare condition characterized by the classic triad of respiratory, nail and lymphatic involvement.Diagnosis remains clinical with no confirmatory tests available; the absence of yellow nails does not preclude the diagnosis.An association with selective IgM deficiency has been infrequently reported.
CONCLUSIONS: Yellow nail syndrome is a rare condition characterized by the classic triad of respiratory, nail and lymphatic involvement.Diagnosis remains clinical with no confirmatory tests available; the absence of yellow nails does not preclude the diagnosis.An association with selective IgM deficiency has been infrequently reported.
摘要：
一名67岁的男子因症状恶化而入院，有IgM缺乏，肺纤维化和支气管扩张的病史。调查显示渗出性胸腔积液伴有快速进展的支气管扩张。尽管过去几位医生进行了广泛的研究，但仍未发现支气管扩张和肺纤维化的潜在诱因，对所有四肢的黄色营养不良性指甲的床边观察显示了诊断。此病例报告有助于提醒临床医生一种罕见的病因尚不确定且尚无治愈方法的医学疾病。该病例与先前的一些病例报告一致，这些病例报告表明与选择性免疫球蛋白缺乏潜在关联。
结论：黄指甲综合征是一种罕见的疾病，其特征是典型的三联症，指甲和淋巴受累。诊断仍是临床诊断，没有确证试验；没有黄色指甲并不排除诊断。很少报道与选择性IgM缺乏症有关。
结论：黄指甲综合征是一种罕见的疾病，其特征是典型的三联症，指甲和淋巴受累。诊断仍是临床诊断，没有确证试验；没有黄色指甲并不排除诊断。很少报道与选择性IgM缺乏症有关。
