Abstract：
Tilapia has a high socioeconomic value in many countries worldwide. However, it has been identified as a zoonotic parasite reservoir. A systematic literature search and meta-analysis were carried out in order to estimate the global prevalence of zoonotic parasites that affect tilapia. The search was performed by three field experts to avoid reviewer bias. Polled prevalence was estimated using a logistic-normal random-effect regression model in the R software. We dealt with the heterogeneity among studies through subgroup analysis, taking into account the continent, country, genus of the host, parasite taxonomic group, sample origin, and type of diagnostic test as moderator variables. Fifty-two eligible articles were identified covering five tilapia genera with a pooled prevalence of 0.14 (95% CI: 0.10−0.20) showed significant heterogeneity (I2 = 98.4; p < 0.001). The subgroup analysis revealed that the most affected host was Sarotherodon, with a prevalence of 0.42 (95% CI: 0.22−0.65). Cestode was the taxonomic group with the largest prevalence (0.40; 95% CI:0.32−0.48), followed by amoeba (0.24; 95% CI: 0.16−0.35) and nematode (0.22; 95% CI: 0.11−0.38), among which, Schyzocotyle spp., Opistorchis spp., Gnathostoma spp. and Vermamoeba spp. have an impact on public health. Significant differences (p < 0.004) were found among continents and countries, with the highest value of prevalence detected in the African continent (0.28; 95% CI: 0.20−0.37), specifically in Tanzania (0.56; 95% CI: 0.22−0.87) and Egypt (0.43; 95% CI: 0.20−0.55). The origin of samples had a significant effect (p < 0.0001) on the detected prevalence, especially from those that showed the highest prevalence (0.24; 95% CI: 0.17−0.33). Finally, there were no differences in prevalence according to the diagnostic test (p = 0.97). Our results provide useful information on the development of epidemiological programs for the control of zoonoses associated with parasites in tilapia and in the design, planning, and implementation of future research.
摘要：
罗非鱼在世界许多国家具有很高的社会经济价值。然而,它已被确定为人畜共患寄生虫水库。进行了系统的文献检索和荟萃分析，以估计影响罗非鱼的人畜共患寄生虫的全球患病率。搜索由三名领域专家进行，以避免审阅者的偏见。使用R软件中的逻辑正态随机效应回归模型估计调查患病率。我们通过亚组分析处理了研究之间的异质性，考虑到大陆，国家,宿主属，寄生虫分类群，样品来源,和诊断测试类型作为调节变量。确定了52篇合格的文章，涵盖了5个罗非鱼属，合并患病率为0.14（95％CI：0.10-0.20），显示出显着的异质性（I2=98.4;p＆lt;0.001）。亚组分析显示，受影响最大的宿主是Sarotherodon，患病率为0.42（95%CI：0.22-0.65）。Cestode是患病率最高的分类组（0.40;95％CI：0.32-0.48），其次是变形虫(0.24;95%CI:0.16-0.35)和线虫(0.22;95%CI:0.11-0.38)，其中,Schyzocotylespp.,Opistorchisspp.,鼻孔口。和Vermamoebaspp.对公众健康有影响。在大陆和国家之间发现了显著差异(p<0.004)，在非洲大陆检测到的患病率最高（0.28；95%CI：0.20-0.37），特别是在坦桑尼亚（0.56；95%CI：0.22-0.87）和埃及（0.43；95%CI：0.20-0.55）。样本来源对检测到的患病率有显著影响(p<0.0001),尤其是那些患病率最高的人群(0.24;95%CI:0.17-0.33)。最后,根据诊断检验,患病率无差异(p=0.97).我们的结果为控制与罗非鱼寄生虫相关的人畜共患病的流行病学计划的制定提供了有用的信息，规划,以及未来研究的实施。
