Abstract：
OBJECTIVE: We report use of cyanoacrylate (N-butyl-Cyanoacrylate) in previously failed retinal reattachment surgeries for chorio-retinal colobomas. We report the surgical technique, its challenges, and long-term outcomes in three patients who underwent the surgery.
METHODS: A chart review of patients with chorio-retinal colobomas and retinal detachment repair with cyanoacrylate at a tertiary eye care center in Nepal. Cyanoacrylate was used to seal colobomatous retinal breaks in eyes which had undergone multiple retinal surgeries with failed outcome.
RESULTS: Three eyes that were operated using cyanoacrylate were included. All three patients had attached retina and none of the patients required a long-term tamponading agent. None of the patients underwent head positioning following the surgery. All of the patients had a visual acuity gain of 3/60 or more at the end of 8 months. No adverse or inflammatory reactions were noted.
CONCLUSIONS: We demonstrate that cyanoacrylate is safe and less resource-demanding without a requirement of second surgery to remove a tamponading agent. It could be helpful in eyes with persistent retinal detachment in colobomatous eyes. Because we were able to achieve favorable outcomes without head positioning, we believe it may also be helpful in patients who are not suitable for positioning because of bodily or bony deformities and in retinal detachment with other coexisting trauma.
METHODS: A chart review of patients with chorio-retinal colobomas and retinal detachment repair with cyanoacrylate at a tertiary eye care center in Nepal. Cyanoacrylate was used to seal colobomatous retinal breaks in eyes which had undergone multiple retinal surgeries with failed outcome.
RESULTS: Three eyes that were operated using cyanoacrylate were included. All three patients had attached retina and none of the patients required a long-term tamponading agent. None of the patients underwent head positioning following the surgery. All of the patients had a visual acuity gain of 3/60 or more at the end of 8 months. No adverse or inflammatory reactions were noted.
CONCLUSIONS: We demonstrate that cyanoacrylate is safe and less resource-demanding without a requirement of second surgery to remove a tamponading agent. It could be helpful in eyes with persistent retinal detachment in colobomatous eyes. Because we were able to achieve favorable outcomes without head positioning, we believe it may also be helpful in patients who are not suitable for positioning because of bodily or bony deformities and in retinal detachment with other coexisting trauma.
摘要：
目的：我们报告了在先前失败的视网膜复位手术中使用氰基丙烯酸酯（N-丁基-氰基丙烯酸酯）治疗绒毛膜-视网膜瘤。我们报道了手术技术，其挑战,和3例接受手术的患者的长期结局。
方法：在尼泊尔一家三级眼科护理中心对绒毛膜-视网膜缺损和氰基丙烯酸酯修复视网膜脱离的患者进行图表回顾。氰基丙烯酸酯用于密封眼睛中的结肠腺瘤性视网膜破裂，这些视网膜破裂经历了多次视网膜手术，结果失败。
结果:包括使用氰基丙烯酸酯手术的三只眼睛。所有三名患者都有视网膜附着，没有一名患者需要长期填塞剂。手术后没有患者进行头部定位。在8个月结束时，所有患者的视力均增加了3/60或更多。未发现不良反应或炎性反应。
结论：我们证明氰基丙烯酸酯是安全的，不需要第二次手术来去除填塞剂。它可能对结肠瘤眼中持续性视网膜脱离的眼睛有所帮助。因为我们能够在没有头部定位的情况下取得有利的结果，我们认为，对于因身体或骨骼畸形以及与其他共存创伤的视网膜脱离而不适合定位的患者，该方法也可能有帮助。
方法：在尼泊尔一家三级眼科护理中心对绒毛膜-视网膜缺损和氰基丙烯酸酯修复视网膜脱离的患者进行图表回顾。氰基丙烯酸酯用于密封眼睛中的结肠腺瘤性视网膜破裂，这些视网膜破裂经历了多次视网膜手术，结果失败。
结果:包括使用氰基丙烯酸酯手术的三只眼睛。所有三名患者都有视网膜附着，没有一名患者需要长期填塞剂。手术后没有患者进行头部定位。在8个月结束时，所有患者的视力均增加了3/60或更多。未发现不良反应或炎性反应。
结论：我们证明氰基丙烯酸酯是安全的，不需要第二次手术来去除填塞剂。它可能对结肠瘤眼中持续性视网膜脱离的眼睛有所帮助。因为我们能够在没有头部定位的情况下取得有利的结果，我们认为，对于因身体或骨骼畸形以及与其他共存创伤的视网膜脱离而不适合定位的患者，该方法也可能有帮助。
