PDF(Pubmed)
Abstract：
BACKGROUND: Parkinson\'s disease (PD) is a common neurogenerative disease marked by the characteristic triad of bradykinesia, rigidity, and tremor. A significant percentage of patients with PD also demonstrate postural abnormalities (camptocormia) that limit ambulation and accelerate degenerative pathologies of the spine. Although deep brain stimulation (DBS) is a well-established treatment for the motor fluctuations and tremor seen in PD, the efficacy of DBS on postural abnormalities in these patients is less clear.
METHODS: The authors present a patient with a history of PD and prior lumbosacral fusion who underwent bilateral subthalamic nucleus DBS and experienced immediate improvement in sagittal alignment and subjective relief of mechanical low-back pain.
CONCLUSIONS: DBS may improve postural abnormalities seen in PD and potentially delay or reduce the need for spinal deformity surgery.
METHODS: The authors present a patient with a history of PD and prior lumbosacral fusion who underwent bilateral subthalamic nucleus DBS and experienced immediate improvement in sagittal alignment and subjective relief of mechanical low-back pain.
CONCLUSIONS: DBS may improve postural abnormalities seen in PD and potentially delay or reduce the need for spinal deformity surgery.
摘要：
背景：帕金森病（PD）是一种常见的神经退行性疾病，其特征是运动迟缓三联征，刚性,和震颤。很大比例的PD患者还表现出姿势异常（喜忧乐），这限制了步行并加速了脊柱的退行性病变。尽管深部脑刺激（DBS）是一种公认的治疗PD运动波动和震颤的方法，DBS对这些患者姿势异常的疗效尚不清楚.
方法：作者介绍了一名有PD病史且先前有腰骶骨融合的患者，该患者接受了双侧丘脑下核DBS治疗，矢状面对准立即得到改善，并主观缓解了机械性下腰痛。
结论：DBS可以改善PD患者的姿势异常，并可能延迟或减少脊柱畸形手术的需要。
方法：作者介绍了一名有PD病史且先前有腰骶骨融合的患者，该患者接受了双侧丘脑下核DBS治疗，矢状面对准立即得到改善，并主观缓解了机械性下腰痛。
结论：DBS可以改善PD患者的姿势异常，并可能延迟或减少脊柱畸形手术的需要。
