{Reference Type}: Journal Article
{Title}: Improvement in sagittal alignment and mechanical low-back pain following deep brain stimulation for Parkinson's disease: illustrative case.
{Author}: Guerrero JR;Bhenderu LS;Taghlabi KM;Cruz-Garza JG;Saifi C;Faraji AH;
{Journal}: J Neurosurg Case Lessons
{Volume}: 4
{Issue}: 17
{Year}: Oct 2022 24
暂无{DOI}: 10.3171/CASE22357
{Abstract}: <B>BACKGROUND: </B>Parkinson's disease (PD) is a common neurogenerative disease marked by the characteristic triad of bradykinesia, rigidity, and tremor. A significant percentage of patients with PD also demonstrate postural abnormalities (camptocormia) that limit ambulation and accelerate degenerative pathologies of the spine. Although deep brain stimulation (DBS) is a well-established treatment for the motor fluctuations and tremor seen in PD, the efficacy of DBS on postural abnormalities in these patients is less clear.<BR><B>METHODS: </B>The authors present a patient with a history of PD and prior lumbosacral fusion who underwent bilateral subthalamic nucleus DBS and experienced immediate improvement in sagittal alignment and subjective relief of mechanical low-back pain.<BR><B>CONCLUSIONS: </B>DBS may improve postural abnormalities seen in PD and potentially delay or reduce the need for spinal deformity surgery.