关键词: Artificial intelligence Colorectal cancer Computed tomography Imaging Positron emission tomography Radiomics Standardisation

Mesh : Humans Consensus Artificial Intelligence Reproducibility of Results Rectal Neoplasms Colonic Neoplasms

来  源:   DOI:10.1016/j.ejca.2022.09.012

Abstract:
Treatment monitoring in metastatic colorectal cancer (mCRC) relies on imaging to evaluate the tumour burden. Response Evaluation Criteria in Solid Tumors provide a framework on reporting and interpretation of imaging findings yet offer no guidance on a standardised imaging protocol tailored to patients with mCRC. Imaging protocol heterogeneity remains a challenge for the reproducibility of conventional imaging end-points and is an obstacle for research on novel imaging end-points.
Acknowledging the recently highlighted potential of radiomics and artificial intelligence tools as decision support for patient care in mCRC, a multidisciplinary, international and expert panel of imaging specialists was formed to find consensus on mCRC imaging protocols using the Delphi method.
Under the guidance of the European Organisation for Research and Treatment of Cancer (EORTC) Imaging and Gastrointestinal Tract Cancer Groups, the European Society of Oncologic Imaging (ESOI) and the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), the EORTC-ESOI-ESGAR core imaging protocol was identified.
This consensus protocol attempts to promote standardisation and to diminish variations in patient preparation, scan acquisition and scan reconstruction. We anticipate that this standardisation will increase reproducibility of radiomics and artificial intelligence studies and serve as a catalyst for future research on imaging end-points. For ongoing and future mCRC trials, we encourage principal investigators to support the dissemination of these imaging standards across recruiting centres.
摘要:
转移性结直肠癌(mCRC)的治疗监测依赖于成像来评估肿瘤负荷。实体瘤的反应评估标准提供了一个报告和解释成像发现的框架,但没有提供针对mCRC患者量身定制的标准化成像方案的指导。成像协议异质性仍然是传统成像终点的再现性的挑战,并且是对新型成像终点研究的障碍。
承认最近强调的影像组学和人工智能工具作为mCRC患者护理决策支持的潜力,多学科,成立了国际和专家成像专家小组,以使用Delphi方法就mCRC成像方案达成共识。
在欧洲癌症研究和治疗组织(EORTC)成像和胃肠道癌症小组的指导下,欧洲肿瘤成像学会(ESOI)和欧洲胃肠和腹部放射学学会(ESGAR),确定了EORTC-ESOI-ESGAR核心成像方案.
本共识方案试图促进标准化并减少患者准备的变化。扫描采集和扫描重建。我们预计这种标准化将提高影像组学和人工智能研究的可重复性,并作为未来成像终点研究的催化剂。对于正在进行和未来的mCRC试验,我们鼓励主要调查人员支持在招聘中心传播这些成像标准。
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