Abstract：
Prenatal diagnoses of cystic malformations of the posterior fossa mainly encompass arachnoid cysts, Blake\'s pouch cysts and Dandy-Walker syndrome. To date, vermian cysts have not been reported prenatally.
To report a series of fetuses with a vermian cyst.
This was a single-center retrospective study conducted from 2012 to 2021. We included all fetuses presenting with a vermian cyst and excluded all other types of posterior fossa cyst. The cyst was visible at prenatal ultrasound (US) and/or magnetic resonance imaging (MRI). Postnatal imaging and/or clinical outcome data were available.
Sixteen fetuses fulfilled the inclusion criteria with a strong female predominance (n=13). US and MRI were performed at a mean gestational age of 29+5 and 33+1 weeks, respectively. In all patients, the cyst was in the vermian horizontal fissure. The mean longest dimension was about 10 mm. The vermis and other posterior fossa structures were otherwise normal. At postnatal imaging, 13 children underwent brain imaging including 11 MRIs with complete regression (n=9), stability (n=1) and increase in size (n=3) of the cyst. Psychomotor development was normal in 14 children. One child (with an inner ear malformation) showed a slight delay in walking and language acquisition. Slight walking ataxia was present in another child.
We report 16 fetuses with posterior fossa cysts located within the vermis at the level of the horizontal fissure, diagnosed at US and/or MRI and carrying an overall excellent neurological prognosis.
To report a series of fetuses with a vermian cyst.
This was a single-center retrospective study conducted from 2012 to 2021. We included all fetuses presenting with a vermian cyst and excluded all other types of posterior fossa cyst. The cyst was visible at prenatal ultrasound (US) and/or magnetic resonance imaging (MRI). Postnatal imaging and/or clinical outcome data were available.
Sixteen fetuses fulfilled the inclusion criteria with a strong female predominance (n=13). US and MRI were performed at a mean gestational age of 29+5 and 33+1 weeks, respectively. In all patients, the cyst was in the vermian horizontal fissure. The mean longest dimension was about 10 mm. The vermis and other posterior fossa structures were otherwise normal. At postnatal imaging, 13 children underwent brain imaging including 11 MRIs with complete regression (n=9), stability (n=1) and increase in size (n=3) of the cyst. Psychomotor development was normal in 14 children. One child (with an inner ear malformation) showed a slight delay in walking and language acquisition. Slight walking ataxia was present in another child.
We report 16 fetuses with posterior fossa cysts located within the vermis at the level of the horizontal fissure, diagnosed at US and/or MRI and carrying an overall excellent neurological prognosis.
摘要：
背景：产前诊断后颅窝囊性畸形主要包括蛛网膜囊肿，Blake的囊袋囊肿和Dandy-Walker综合征.迄今为止,Vermian囊肿尚未在产前报告。
目的：报告一系列胎儿的Vermian囊肿。
方法：这是2012年至2021年进行的单中心回顾性研究。我们纳入了所有出现Vermian囊肿的胎儿，并排除了所有其他类型的后窝囊肿。在产前超声（US）和/或磁共振成像（MRI）中可见囊肿。产后影像学和/或临床结果数据可用。
结果：16例胎儿符合纳入标准，女性占优势（n=13）。US和MRI在平均胎龄29+5和33+1周进行，分别。在所有患者中，囊肿位于Vermian水平裂中。平均最长尺寸为约10mm。Vermis和其他后颅窝结构正常。在产后成像时，13名儿童接受了脑成像，包括11名完全回归的MRI（n=9），囊肿的稳定性（n=1）和大小增加（n=3）。14名儿童的精神运动发育正常。一名儿童（患有内耳畸形）在行走和语言习得方面略有延迟。另一个孩子出现了轻微的行走性共济失调。
结论：我们报告了16个胎儿的后窝囊肿位于水平裂水平的疣内，在US和/或MRI诊断，并具有良好的神经系统预后。
目的：报告一系列胎儿的Vermian囊肿。
方法：这是2012年至2021年进行的单中心回顾性研究。
结果：16例胎儿符合纳入标准，女性占优势（n=13）。
结论：我们报告了16个胎儿的后窝囊肿位于水平裂水平的疣内，
