Abstract：
A dire complication associated with chronic epilepsy is abrupt premature death, currently referred to as sudden unexpected death in epilepsy (SUDEP). Although the traditional view has been that SUDEP is due primarily to peri-ictal respiratory failure leading to cardiac asystole, mounting evidence implicates accelerated heart disease, leading to an \"epileptic heart\" condition, especially after age 40, as another potential cause of abrupt premature death, although cardiac death is specifically excluded by the standard definition of SUDEP. Sudden cardiac death in epilepsy carries a 2.8-fold greater risk than in the general population and is 4.5 times more frequent than SUDEP. This review will discuss the rationale for routine use of electrocardiograms to assess cardiac risk in patients with epilepsy and the impact of epilepsy treatments, namely antiseizure medications and chronic vagus nerve stimulation.
摘要：
与慢性癫痫相关的可怕并发症是突然过早死亡，目前被称为癫痫猝死（SUDEP）。尽管传统观点认为SUDEP主要是由于围发作期呼吸衰竭导致心脏停搏，越来越多的证据暗示心脏病加速，导致“癫痫心脏”状况，特别是在40岁以后，作为突然过早死亡的另一个潜在原因，尽管SUDEP的标准定义明确排除了心脏死亡。癫痫患者心源性猝死的风险是普通人群的2.8倍，是SUDEP的4.5倍。这篇综述将讨论常规使用心电图来评估癫痫患者的心脏风险的基本原理以及癫痫治疗的影响。即抗癫痫药物和慢性迷走神经刺激。
