Current international literature was reviewed to describe the clinical behavior of human papillomavirus in men.
Internationally, the overall prevalence of HPV DNA is 50.8%, HPV considered high risk are 14 types. Prevalence of HPV DNA in invasive penile cancer ranges from 33.1% to 47%. HPV-16 has been the most frequent (68.3%), followed by HPV-6 (8.1%) and HPV-18 (6.9%). Positive HPV is described as an independent prognostic factor for cancer-specific survival.
It is not clear why HPV infection has a predilection in specific areas of the genital tract. However, it is important to note that there are factors that increase the risk of HPV infection.
方法:综述了目前的国际文献来描述人乳头瘤病毒在男性中的临床行为。
结果:国际上,HPVDNA的总体患病率为50.8%,HPV被认为是高风险的14种类型。浸润性阴茎癌中HPVDNA的患病率为33.1%至47%。HPV-16是最常见的(68.3%),其次是HPV-6(8.1%)和HPV-18(6.9%)。HPV阳性被描述为癌症特异性存活的独立预后因素。
结论:目前尚不清楚为什么HPV感染在生殖道的特定区域有优势。然而,重要的是要注意,有一些因素会增加HPV感染的风险。