PDF(Pubmed)
Abstract：
The coronavirus pandemic has caused a devastating impact across the planet. Millions of lives lost and economic structures are struggling to remain afloat. Clinical effects of SARS CoV-2 virus include tiredness, fatigue, headache, cough, loss of appetite, fever, loss of sensations of taste, and smell as well as other respiratory difficulties. Pulmonary complications of coronavirus infections result in severe pneumonia with the final sequelae being sepsis, and end-stage respiratory failure. Further cardiovascular, neurological, hematological, and gastrointestinal complications build up to cause the demise of the immune system ultimately leading to death of the affected individual. The attack of the virus and the resultant reaction of the epithelial cells lining the respiratory tract have been in the limelight of most studies pertaining to the pandemic. However, a lesser number of studies have detailed the muscular and osseous pathologies that appear post-coronavirus infection. Inflammation post-infection, across the organ systems, may appear as a link to bone and joint pathology. Myalgia is a typical COVID-19 infection symptom. On the contrary, other musculoskeletal signs have very seldom been reported. Multimodality imaging techniques stand a chance at showing the diagnosis and the degree of follow-up after evaluation. Apart from myalgia, there are cases of arthralgia, myopathies, and neuropathies. According to numerous reports, there is the possibility of a link between the current drug regimen used to treat the SARS-CoV-2 infection and the musculoskeletal manifestations observed. In this study, we aim to shed light on the coronavirus pandemic and its association to various musculoskeletal manifestations, provide a different perspective of the infected patients, and address the major points that a clinician must take care while administering care to the patient. We will also address the present treatment in line with the various musculoskeletal symptoms observed.
摘要：
冠状病毒大流行在整个地球上造成了毁灭性的影响。数百万人丧生，经济结构正在努力维持生计。SARSCoV-2病毒的临床效果包括疲倦，疲劳,头痛,咳嗽,食欲不振,发烧,失去味觉，和气味以及其他呼吸困难。冠状病毒感染的肺部并发症会导致严重的肺炎，最后的后遗症是败血症，和终末期呼吸衰竭。进一步心血管，神经学,血液学,胃肠道并发症的积累导致免疫系统的死亡，最终导致受影响的个体死亡。在大多数与大流行有关的研究中，病毒的攻击和呼吸道内膜上皮细胞的反应一直是人们关注的焦点。然而,较少数量的研究详细介绍了冠状病毒感染后出现的肌肉和骨病理。感染后炎症，整个器官系统，可能与骨骼和关节病理有关。肌痛是一种典型的COVID-19感染症状。相反,其他肌肉骨骼体征很少被报道。多模态成像技术有机会显示诊断和评估后的随访程度。除了肌痛,有关节痛的病例，肌病,和神经病。根据众多报道，目前用于治疗SARS-CoV-2感染的药物方案与观察到的肌肉骨骼表现之间可能存在联系.在这项研究中,我们的目标是阐明冠状病毒大流行及其与各种肌肉骨骼表现的关联，为受感染的患者提供不同的视角，并解决临床医生在对患者进行护理时必须注意的主要问题。我们还将根据观察到的各种肌肉骨骼症状来处理本治疗。
