关键词: anticancer bacteriocin cancer lactic acid bacteria new treatment

来  源:   DOI:10.3390/cancers14194758

Abstract:
Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines.
摘要:
癌症被认为是最常见和最主要的死亡原因之一。尽管有针对癌细胞的常规治疗方法,目前的治疗方法不是癌症的最佳治疗方法,因为它们有可能对身体造成各种不必要的副作用。因此,这促使人们寻找替代治疗方法,而不会表现出任何额外的副作用.针对癌症的有希望的新型治疗候选物之一是由称为细菌素的细菌产生的抗微生物肽。它是一种无毒的肽,据报道显示出对癌细胞系的效力。实验研究概述了细菌素对各种癌细胞系的治疗潜力。在这篇评论文章中,本文重点介绍了各种细菌素及其细胞毒性作用,作为针对各种癌细胞系的治疗剂的作用方式和功效。
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