PDF(Pubmed)
Abstract：
This study characterizes the subcortical auditory brainstem response (speech-ABR) and cortical auditory processing (P1 and Mismatch Negativity; MMN) to speech sounds and their relationship to autistic traits and sensory features within the same group of autistic children (n = 10) matched on age and non-verbal IQ to their typically developing (TD) peers (n = 21). No speech-ABR differences were noted, but autistic individuals had larger P1 and faster MMN responses. Correlations revealed that larger P1 amplitudes and MMN responses were associated with greater autistic traits and more sensory features. These findings highlight the complexity of the auditory system and its relationships to behaviours in autism, while also emphasizing the importance of measurement and developmental matching.
摘要：
这项研究描述了同一组自闭症儿童（n=10）对语音的皮层下听觉脑干反应（语音-ABR）和皮层听觉处理（P1和失配否定性；MMN）及其与自闭症特征和感觉特征的关系年龄和非语言智商与典型发育（TD）同龄人（n=21）相匹配。没有注意到语音-ABR差异，但是自闭症患者的P1更大，MMN反应更快。相关性表明，较大的P1振幅和MMN反应与更大的自闭症特征和更多的感觉特征相关。这些发现强调了听觉系统的复杂性及其与自闭症行为的关系，同时也强调了测量和发展匹配的重要性。
