关键词: basal cell carcinoma of scalp bcc concurrent non-melanoma skin cancers incidence and risk factors ktr post-renal transplant post-transplant malignancy renal transplant scc squamous cell carcinoma

来  源:   DOI:10.7759/cureus.28764   PDF(Pubmed)

Abstract:
In solid organ transplant patients, non-melanoma skin cancer remains a leading cause of mortality. The most common skin malignancies in solid organ transplant patients are squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). In organ transplant patients, SCC is 100 times more prevalent, and BCC is 10 times more prevalent than in the general population. Many risk factors for developing such malignancies are equivalent to those in the general population. However, in the transplant population, such cancers occur at an earlier age, act more aggressively, and often appear at multiple locations. Thus, assiduousness on the patient\'s part and healthcare providers is the highest priority. The concurrence of SCC and BCC together is rarely encountered in a post-transplant individual. We report a rare case of coexistence of SCC and BCC in the same patient. A 63-year-old man had been diagnosed with SCC and BCC simultaneously by a punch biopsy performed at two different scalp lesions of different diameters. This review describes an unusual occurrence of both skin cancers concurrently in a kidney transplant recipient.
摘要:
在实体器官移植患者中,非黑色素瘤皮肤癌仍然是导致死亡的主要原因.实体器官移植患者中最常见的皮肤恶性肿瘤是鳞状细胞癌(SCC)和基底细胞癌(BCC)。在器官移植患者中,SCC的患病率要高出100倍,BCC的患病率是普通人群的10倍。发生此类恶性肿瘤的许多风险因素与普通人群中的风险因素相同。然而,在移植人群中,这种癌症发生在更早的年龄,行动更积极,并且经常出现在多个位置。因此,病人和医疗保健提供者的刻苦是最优先考虑的。在移植后的个体中很少遇到SCC和BCC一起并发的情况。我们报告了同一患者中SCC和BCC共存的罕见病例。通过对两个不同直径的头皮病变进行穿刺活检,同时诊断出一名63岁的男子患有SCC和BCC。这篇综述描述了肾移植受者中两种皮肤癌同时发生的罕见情况。
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