Abstract：
Non-genital warts are benign cutaneous growths caused by infection with the human papillomavirus. Although warts can resolve spontaneously, patients might seek treatment due to discomfort or social ostracism. This review summarises high-quality studies investigating the efficacy of chemical and physical destructive wart therapies.
We performed a literature review (up to June 2021) of published articles for wart management from MEDLINE and Embase databases. We considered systematic reviews, randomised controlled trials (RCTs), cohort studies and case series. We included studies that investigated chemical or physical destructive therapies.
Fifteen therapies were evaluated and included salicylic acid, cryotherapy, silver nitrate, phenol, cantharidin, glycolic acid, pyruvic acid, citric acid, formic acid, trichloroacetic acid, monochloroacetic acid, zinc, laser, surgery and electrocautery. Very few treatment options have been studied through RCTs.
To attenuate transmission, hygienic practices need to be adopted in conjunction with any treatment. Important considerations when treating patients with warts include the location of the wart, the evidence supporting the proposed treatment and potential adverse effects of treatment.
We performed a literature review (up to June 2021) of published articles for wart management from MEDLINE and Embase databases. We considered systematic reviews, randomised controlled trials (RCTs), cohort studies and case series. We included studies that investigated chemical or physical destructive therapies.
Fifteen therapies were evaluated and included salicylic acid, cryotherapy, silver nitrate, phenol, cantharidin, glycolic acid, pyruvic acid, citric acid, formic acid, trichloroacetic acid, monochloroacetic acid, zinc, laser, surgery and electrocautery. Very few treatment options have been studied through RCTs.
To attenuate transmission, hygienic practices need to be adopted in conjunction with any treatment. Important considerations when treating patients with warts include the location of the wart, the evidence supporting the proposed treatment and potential adverse effects of treatment.
摘要：
非生殖器疣是由人乳头瘤病毒感染引起的良性皮肤生长。虽然疣可以自发解决，患者可能因不适或社会排斥而寻求治疗。这篇综述总结了研究化学和物理破坏性疣疗法疗效的高质量研究。
我们对MEDLINE和Embase数据库中已发表的疣管理文章进行了文献综述（截至2021年6月）。我们考虑了系统评价，随机对照试验（RCT），队列研究和病例系列。我们纳入了研究化学或物理破坏性疗法的研究。
评估了15种疗法，包括水杨酸，冷冻疗法,硝酸银,苯酚,cantharidin,乙醇酸,丙酮酸,柠檬酸,甲酸,三氯乙酸,一氯乙酸,锌，激光,手术和电灼术.通过RCT研究的治疗方案很少。
要衰减传输，任何治疗都需要采用卫生习惯。治疗疣患者时的重要考虑因素包括疣的位置，支持拟议治疗的证据和治疗的潜在不良反应。
我们对MEDLINE和Embase数据库中已发表的疣管理文章进行了文献综述（截至2021年6月）。我们考虑了系统评价，随机对照试验（RCT），队列研究和病例系列。我们纳入了研究化学或物理破坏性疗法的研究。
评估了15种疗法，包括水杨酸，冷冻疗法,硝酸银,苯酚,cantharidin,乙醇酸,丙酮酸,柠檬酸,甲酸,三氯乙酸,一氯乙酸,锌，激光,手术和电灼术.通过RCT研究的治疗方案很少。
要衰减传输，任何治疗都需要采用卫生习惯。治疗疣患者时的重要考虑因素包括疣的位置，支持拟议治疗的证据和治疗的潜在不良反应。
