UNASSIGNED: A comprehensive search of several databases from database inception to June 30, 2021, was designed and conducted by an experienced librarian with input from study investigators.
UNASSIGNED: Study inclusion criteria encompassed all study designs evaluating TBI associated with MAHB. Two independent reviewers reviewed all titles, abstracts, and full texts.
UNASSIGNED: Data were extracted by 2 independent reviewers, and results were summarized descriptively.
UNASSIGNED: Of 407 eligible studies, 13 met inclusion criteria. All included studies were case reports from multiple countries describing a case of moderate-severe TBI occurring as a direct consequence of MAHB. Of the individuals reported (n=13), they had 1 or more of the following: traumatic subdural hematoma (n=8), internal carotid artery dissection (n=2), basilar artery thrombosis (n=2), traumatic vertebral artery aneurism (n=1), or intracerebral hemorrhage (n=1). No studies were found involving mild TBI after MAHB.
UNASSIGNED: This scoping review suggests that MAHB is a risk factor for moderate-severe TBI, although the incidence of mild TBI after MAHB remains unknown. Additional research is needed to understand the association of TBI after MAHB through the spectrum of injury severity, including the potential sequelae of multiple subconcussive injuries.
UNASSIGNED:从数据库开始到2021年6月30日的几个数据库的全面搜索是由经验丰富的图书馆员在研究调查人员的输入下设计和进行的。
UASSIGNED:研究纳入标准包括所有评估与MAHB相关的TBI的研究设计。两名独立审稿人审查了所有标题,摘要,和全文。
UNASSIGNED:数据由2名独立审稿人提取,并对结果进行了描述性总结。
未经评估:在407项符合条件的研究中,13符合纳入标准。所有纳入的研究都是来自多个国家的病例报告,描述了一例由MAHB直接导致的中重度TBI。在报告的个体中(n=13),他们有一个或多个以下:外伤性硬膜下血肿(n=8),颈内动脉夹层(n=2),基底动脉血栓形成(n=2),外伤性椎动脉动脉瘤(n=1),或脑出血(n=1)。没有发现涉及MAHB后轻度TBI的研究。
未经评估:这项范围审查表明,MAHB是中重度TBI的危险因素,尽管MAHB后轻度TBI的发生率尚不清楚。需要更多的研究来了解MAHB后TBI通过损伤严重程度谱的关联,包括多发性脑震荡损伤的潜在后遗症。