PDF(Pubmed)
Abstract：
Nanotechnology is the emerging and advance field of research for the diagnosis and treatment of various diseases. With the development of nanotechnology, different nanoparticles are used in the treatment of cancer due to their unique optical properties, excellent biocompatibility, surface effects, and small size effects. Nanoparticles are the particles which have the particular size from 1 to 100 nm. These nanoparticles are zero dimension, one dimension, two dimension and three dimension etc. In present scenario a variety of research is focused on the tailored synthesis of nanoparticles for medicinal applications that can be used for cancer treatment based on the morphology, composition, interaction with target cell. The gastrointestinal (GI) tumors are found one of the deadest cancer types with highest reoccurrence rates. The diagnosis and treatment of gastrointestinal cancer is very challenging due to its deep location and complicated surgery. Nanotechnology provides fast diagnosis and immediate treatment for the gastrointestinal disease. A variety of nanomaterials are used for the diagnosis and treatment of GI disease. Nanoparticles target directly to the tumor cell as diagnostic and therapeutic tools facilitating the identification and removal of tumor cells. A number of nanoparticles are developed for the uses are quantum dots (QDs), carbon nanotubes (CNTs), metallic nanoparticles (MNPs), Dendrimers etc. This review article gives an overview of the most promising nanomaterials used for the diagnosis and treatment of GI diseases. This review attempts to incorporate numerous uses for the most current nanomaterials, which have great potential for treating gastrointestinal diseases.
摘要：
纳米技术是用于诊断和治疗各种疾病的新兴和先进的研究领域。随着纳米技术的发展,由于其独特的光学特性，不同的纳米粒子被用于治疗癌症，优异的生物相容性，表面效应,和小尺寸效果。纳米颗粒是具有1至100nm的特定尺寸的颗粒。这些纳米粒子是零维度的，一维,二维和三维等。在目前的情况下，各种研究都集中在定制的纳米颗粒的合成，用于医学应用，可用于基于形态学的癌症治疗，composition,与靶细胞相互作用。发现胃肠(GI)肿瘤是具有最高复发率的最致命的癌症类型之一。胃肠道肿瘤因其部位深、手术复杂,其诊断和治疗具有很大的挑战性。纳米技术为胃肠道疾病提供了快速诊断和即时治疗。多种纳米材料被用于胃肠道疾病的诊断和治疗。纳米颗粒直接靶向肿瘤细胞作为诊断和治疗工具，促进肿瘤细胞的识别和去除。许多纳米粒子被开发用于量子点（QD），碳纳米管(CNTs),金属纳米粒子（MNPs），树枝状等.这篇综述文章概述了最有前途的纳米材料用于胃肠道疾病的诊断和治疗。这篇综述试图结合当前纳米材料的许多用途，具有治疗胃肠道疾病的巨大潜力。
